Cefamandole

Suppliers

Names

[ CAS No. ]:
34444-01-4

[ Name ]:
Cefamandole

[Synonym ]:
cefamandol
MFCD00056872
7-[(2-Hydroxy-2-phenylacetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Florfenicol-d3 AMine
CEFAMANDOLE
cephadole
cephamandole
cefadole
EINECS 252-030-0

Chemical & Physical Properties

[ Density]:
1.75 g/cm3

[ Molecular Formula ]:
C18H18N6O5S2

[ Molecular Weight ]:
462.50300

[ Exact Mass ]:
462.07800

[ PSA ]:
201.14000

[ LogP ]:
0.10320

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI0383700
CHEMICAL NAME :
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-3- (((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6-alpha,7-beta(R*)))-
CAS REGISTRY NUMBER :
34444-01-4
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H18-N6-O5-S2
MOLECULAR WEIGHT :
462.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 gm/kg/5D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,660,1980 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
30 gm/kg
SEX/DURATION :
male 30 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 8,280,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3194 No. of Facilities: 299 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 16094 (estimated) No. of Female Employees: 13604 (estimated)

Related Compounds

  • cefamandole
  • cefamandole
  • CefamandoleNafate
  • Cefamandole Sodium
  • cefamandole sodium
  • cefamandole lithium
  • rac-2-[(1R,2S)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentaneamido]cyclopentyl]acetic acid
  • rac-2-[(1R,2S)-2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentaneamido]cyclopentyl]acetic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanoyl]thiomorpholine-2-carboxylic acid
  • 4-[2-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]thiomorpholine-2-carboxylic acid
  • 3-[benzyl(methyl)amino]-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cycloheptyl]formamido}propanoic acid
  • 3-[benzyl(methyl)amino]-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylcyclohexyl]formamido}propanoic acid
  • 3-[benzyl(methyl)amino]-2-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-1-yl]acetamido}propanoic acid
  • 3-[benzyl(methyl)amino]-2-{[3-chloro-5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]formamido}propanoic acid
  • 3-cyclopropyl-4-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}butanoic acid
  • 3-cyclopropyl-4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]butanoic acid
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