PJ34 HCl

Suppliers

Names

[ Name ]:
PJ34 HCl

[Synonym ]:
2-Phenanthridineacetamide, 5,6-dihydro-N,N-dimethyl-6-oxo-, hydrochloride (1:1)
2-(Dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide hydrochloride
PARP Inhibitor VIII,PJ34
s7300
PJ-34 hydrochloride hydrate
PJ 34 Hydrochloride
N,N-Dimethyl-2-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide hydrochloride (1:1)
Acetamide (N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)
N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride
N,N-Dimethyl-2-(6-oxo-5,6-dihydro-2-phenanthridinyl)acetamide hydrochloride (1:1)
PJ34 HCl
PJ34 (hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
539.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₈ClN₃O₂

[ Molecular Weight ]:
331.80

[ Flash Point ]:
279.9ºC

[ PSA ]:
53.17000

[ LogP ]:
3.11400

[ Appearance of Characters ]:
white to yellow

[ Storage condition ]:
Desiccate at RT

[ Water Solubility ]:
H2O: soluble22mg/mL

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Ultraviolet radiation signaling through TLR4/MyD88 constrains DNA repair and plays a role in cutaneous immunosuppression.

J. Immunol. 194(7) , 3127-35, (2015)

UV radiation (UVR) induces DNA damage, leading to the accumulation of mutations in epidermal keratinocytes and immunosuppression, which contribute to the development of nonmelanoma skin cancer. We rep...

Poly-ADP-ribosylation of HMGB1 regulates TNFSF10/TRAIL resistance through autophagy.

Autophagy 11(2) , 214-24, (2015)

Both apoptosis ("self-killing") and autophagy ("self-eating") are evolutionarily conserved processes, and their crosstalk influences anticancer drug sensitivity and cell death. However, the underlying...

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation.

Nat. Med. 7 , 108, (2001)

Diabetic patients frequently suffer from retinopathy, nephropathy, neuropathy and accelerated atherosclerosis. The loss of endothelial function precedes these vascular alterations. Here we report that...