ETHYL 3-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBOXYLATE HYDROCHLORIDE

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Names

[ CAS No. ]:
34467-12-4

[ Name ]:
ETHYL 3-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBOXYLATE HYDROCHLORIDE

[Synonym ]:
3-methyl-5,6-dihydro-imidazo[2,1-b]thiazole-2-carboxylic acid ethyl ester,hydrochloride
Imidazo(2,1-b)thiazole-2-carboxylic acid,5,6-dihydro-3-methyl-,ethyl ester,hydrochloride
ethyl 3-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate hydrochloride
ethyl 3-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate hydrochloride(1:1)

Chemical & Physical Properties

[ Boiling Point ]:
318.4ºC at 760mmHg

[ Melting Point ]:
194-195ºC

[ Molecular Formula ]:
C9H13ClN2O2S

[ Molecular Weight ]:
248.73000

[ Flash Point ]:
146.3ºC

[ Exact Mass ]:
248.03900

[ PSA ]:
71.83000

[ LogP ]:
1.18660

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ5928360
CHEMICAL NAME :
Imidazo(2,1-b)thiazole-2-carboxylic acid, 5,6-dihydro-3-methyl-, ethyl ester, hydrochloride
CAS REGISTRY NUMBER :
34467-12-4
LAST UPDATED :
198609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H12-N2-O2-S.Cl-H
MOLECULAR WEIGHT :
248.75
WISWESSER LINE NOTATION :
T55 AN DN FS DUT&J GVO2 H1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,604,1981

Safety Information

[ Safety Phrases ]:
S24/25

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethlenethiourea
  • Ethyl 2-Chloroacetoacetate

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • 6',7'-dihydro-5'H-spiro[1,5-dioxepane-3,4'-thieno[3,2-c]pyridine]
  • rac-(1R,6S)-2-azabicyclo[4.2.0]octan-5-one
  • 5-Amino-2-(2,6-dimethoxybenzyl)-2,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
  • 4-Methyl-1-(1-naphthalenyloxy)-2-pentanamine
  • 6-Phenyl-3-oxabicyclo[3.1.0]hexane-2,4-dione
  • Benzenemethanol, 3-iodo-alpha-methyl-, 1-acetate
  • 3-[1-(Hydroxymethyl)-3-methoxycyclobutyl]-5,5-dimethyloxolan-3-ol
  • 3-(5-Fluoropyridin-3-yl)propanenitrile
  • 4-(Furan-2-yl)-2,2-dimethyl-1,3-oxazinane
  • (1S,4R)-4,7,7-Trimethyl-3-oxo-N-(4-vinylphenyl)-2-oxabicyclo[2.2.1]heptane-1-carboxamide