4-(1-Methylhydrazino)thiazol-2(5H)-one

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Names

[ CAS No. ]:
34551-16-1

[ Name ]:
4-(1-Methylhydrazino)thiazol-2(5H)-one

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Boiling Point ]:
261.4ºC at 760 mmHg

[ Molecular Formula ]:
C4H7N3OS

[ Molecular Weight ]:
145.18300

[ Flash Point ]:
111.9ºC

[ Exact Mass ]:
145.03100

[ PSA ]:
83.99000

[ LogP ]:
0.19310

[ Index of Refraction ]:
1.713

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ7054350
CHEMICAL NAME :
2(5H)-Thiazolone, 4-(1-methylhydrazino)-
CAS REGISTRY NUMBER :
34551-16-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C4-H7-N3-O-S
MOLECULAR WEIGHT :
145.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
616 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 43,213,1980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • monomethylhydrazine
  • 2-oxo-4-thioxothiazolidine
  • 4-IMINO-1,3-THIAZOLIDIN-2-ONE

DownStream

Related Compounds

  • 4-(1,2-Dimethylhydrazino)thiazol-2(5H)-one
  • 4-(1-methylethyl)furan-2(5H)-one
  • 2,4-Thiazolidinedione, 4-(methylhydrazone) (9CI)
  • 4-Hydroxyimino-2-thiazolidinone
  • 2,4-Thiazolidinedione
  • 2(1H)-Pyrimidinone, 4-(1-methylhydrazino)- (7CI,8CI,9CI)
  • 4-(Fluoromethyl)-2-methyl-5-(trifluoromethoxy)pyridin-3-ol
  • 6-(Cyanomethyl)-3-(difluoromethyl)-5-nitropicolinonitrile
  • Tert-butyl 3,3-difluoro-4-oxo-8-azaspiro[4.5]decane-8-carboxylate
  • 2-(Bromomethyl)-5-chloro-3-(trifluoromethoxy)pyridine-6-carboxylic acid
  • 4-Methoxy-4-[3-(2,2,2-trifluoroethyl)-1,2,4-oxadiazol-5-yl]piperidine hydrochloride
  • 3-(Difluoromethyl)-5-formyl-4-nitropicolinonitrile
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 5-hydroxy-2-Thiopheneethanol
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-((5-(furan-3-yl)pyridin-3-yl)methyl)cyclopentanecarboxamide