5-Methylurapidil

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Names

[ CAS No. ]:
34661-85-3

[ Name ]:
5-Methylurapidil

[Synonym ]:
5-Methyl-6[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₃₂ClN₅O₃

[ Molecular Weight ]:
437.96300

[ Exact Mass ]:
437.21900

[ PSA ]:
71.74000

[ LogP ]:
1.90310

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Cell membrane chromatography competitive binding analysis for characterization of α1A adrenoreceptor binding interactions.

Anal. Bioanal. Chem 400(10) , 3625-33, (2011)

A new high α(1A) adrenoreceptor (α(1A)AR) expression cell membrane chromatography (CMC) method was developed for characterization of α(1A)AR binding interactions. HEK293 α(1A) cell line, which express...

Influence of high dietary sodium intake on the functional subtypes of alpha-adrenoceptors in the renal cortical vasculature of Wistar-Kyoto rats.

Auton. Autacoid Pharmacol. 29(1-2) , 25-31, (2009)

1 Increased renal vascular resistance is one renal functional abnormality that contributes to hypertension, and alpha(1)-adrenoceptors play a pivotal role in modulating this renal vascular resistance....

Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus.

Epilepsy Res. 84(2-3) , 97-109, (2009)

The endogenous catecholamine norepinephrine (NE) exhibits anti-epileptic properties, however it is not well understood which adrenergic receptor (AR) mediates this effect. The aim of this study was to...

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