1,3-Bis(methoxycarbonyl)-2-methyl-2-thiopseudoeura

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Names

[ CAS No. ]:
34840-23-8

[ Name ]:
1,3-Bis(methoxycarbonyl)-2-methyl-2-thiopseudoeura

[Synonym ]:
1,3-Bis(methoxycarbonyl)-2-methyl-2-thiopseudoeura
2-Methylisothiourea-1,3-dicarboxylate
Carbamic acid, N,N'-[(methylthio)methylidyne]bis-, dimethyl ester
Dimethyl [(E)-(methylthio)methylylidene]biscarbamate
Dimethyl [(E)-(methylsulfanyl)methylylidene]biscarbamate
MFCD00674104
carbamic acid, N,N'-[(Z)-(methylthio)methylidyne]bis-, dimethyl ester
Dimethyl [(methylsulfanyl)methylylidene]biscarbamate
Dimethyl [(Z)-(methylsulfanyl)methylylidene]biscarbamate
carbamic acid, N,N'-[(E)-(methylthio)methylidyne]bis-, dimethyl ester
EINECS 252-240-2

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
102-105ºC(lit.)

[ Molecular Formula ]:
C6H10N2O4S

[ Molecular Weight ]:
206.220

[ Exact Mass ]:
206.036133

[ PSA ]:
102.29000

[ LogP ]:
1.03

[ Index of Refraction ]:
1.520

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • METHYL THIOPSEUDOUREA SULFATE
  • Methyl chloroformate
  • 2-methyl-2-thiopseudourea sulfate
  • S-Methylisothiourea sulfate
  • Dimethyl sulfate

DownStream

  • Febantel
  • Carbamic acid, N-(6-hydroxy-1H-benzimidazol-2-yl)-, methyl ester
  • Albendazole
  • 4H-Pyrrolo[3,2-d]pyrimidin-4-one,2-amino-3,5-dihydro-
  • Albendazole Oxide
  • 2-Hydroxybenzimidazole
  • 5-Chloro-1H-benzo[d]imidazol-2(3H)-one
  • dimethyl 4-[2-(methoxycarbonylamino)-3H-benzimidazol-5-yl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • 2-((Methoxycarbonyl)amino)-1H-benzo[d]imidazole-5-carboxylic acid
  • methyl N-(5-phenyl-4,5-dihydro-1H-imidazol-2-yl)carbamate

Articles

CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.

Antimicrob. Agents Chemother. 57(11) , 5448-56, (2013)

Albendazole and fenbendazole are broad-spectrum anthelmintics that undergo extensive metabolism to form hydroxyl and sulfoxide metabolites. Although CYP3A and flavin-containing monooxygenase have been...

Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo [3, 2-d] pyrimidines as dual thymidylate synthase and dihydrofolate Gangjee A, et al.

J. Med. Chem. 51(1) , 68-76, (2007)


More Articles

Related Compounds

  • Benzene,1,3-bis(2-methyl-2-propen-1-yl)-2-(2-propen-1-yloxy)-
  • disodium,(1Z,3Z)-N,N'-bis(benzenecarbonothioyl)-N,N'-dimethylpropanedihydrazonate
  • benzyl 7-methyl-5-(4-methylsulfanylphenyl)-2-[[3-(3-nitrophenyl)-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
  • 1,3-bis[(2,6-dichlorophenyl)methyl]-2-methylpyridin-4-one
  • 1,3-bis(2-methyl-4-nitroimidazol-1-yl)propan-2-yl acetate
  • 1,3-bis(2-methyl-1-phenylprop-1-enyl)urea