5'-[[(3S)-3-AMINO-3-CARBOXYPROPYL]METHYLSULFONIO]-5'-DEOXY-ADENOSINE IODIDE

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Names

[ CAS No. ]:
3493-13-8

[ Name ]:
5'-[[(3S)-3-AMINO-3-CARBOXYPROPYL]METHYLSULFONIO]-5'-DEOXY-ADENOSINE IODIDE

[Synonym ]:
EINECS 222-486-5
SAM iodide salt
S-(5'-ADENOSYL)-L-METHIONINE IODIDE
S-ADENOSYL METHIONINE IODIDE SALT
adomet
MFCD00043192
S-(5'-deoxy-5'-adenosyl)methionine iodide
S-adenosylmethionine
SAM-E IODIDE SALT
AdoMet,SAM
S-adenosyl-L-methionine iodide
S-ADENOSYLMETHIONINE IODIDE
S-adenosylmethione

Chemical & Physical Properties

[ Molecular Formula ]:
C15H23IN6O5S

[ Molecular Weight ]:
526.35000

[ Exact Mass ]:
526.05000

[ PSA ]:
207.93000

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 100 mg/mL

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • methyl iodide
  • SAH

DownStream

Articles

In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist.

J. Pharm. Biomed. Anal. 94 , 36-44, (2014)

Structural modification of the GluN2B selective NMDA receptor antagonist ifenprodil led to the 3-benzazepine WMS-1410 with similar GluN2B affinity but higher receptor selectivity. Herein the in vitro ...

Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target.

J. Biol. Chem. 287 , 1426-1434, (2012)

In the malarial parasite Plasmodium falciparum, a multifunctional phosphoethanolamine methyltransferase (PfPMT) catalyzes the methylation of phosphoethanolamine (pEA) to phosphocholine for membrane bi...

DNA methyltransferases: mechanistic models derived from kinetic analysis.

Crit. Rev. Biochem. Mol. Biol. 47(2) , 97-193, (2012)

The sequence-specific transfer of methyl groups from donor S-adenosyl-L-methionine (AdoMet) to certain positions of DNA-adenine or -cytosine residues by DNA methyltransferases (MTases) is a major form...


More Articles


Related Compounds

  • 3-Amino-1-(6-fluoropyridin-3-yl)propan-1-ol
  • 3-ethyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]pyrrolidine-3-carboxylic acid
  • 1-methyl-5-(pyrrolidin-2-yl)-1H-pyrazole hydrochloride
  • 1-[4-(2-methyl-1H-imidazol-1-yl)phenyl]ethan-1-amine dihydrochloride
  • 2-amino-N-methyl-2-(thiophen-3-yl)acetamide
  • 2-Chloro-6-[(3-methylazetidin-3-yl)oxy]phenol
  • 2-(2-Hydroxy-2-methylpropyl)benzene-1,3,5-triol
  • Tert-butyl 2-(1,2-dihydroxyethyl)-5,5-dimethylpiperidine-1-carboxylate
  • 5-(2-Bromo-5-methylphenyl)thiazol-2-amine
  • (3R)-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexanecarbonyl]piperidine-3-carboxylic acid
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