Alda 1

Names

[ CAS No. ]:
349438-38-6

[ Name ]:
Alda 1

[Synonym ]:
N-(1,3,5-trimethylcyclohexyl)pyrrolidine
Pyrrolidine,1-(1,3,5-trimethylcyclohexyl)
Alda-1

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₁Cl₂NO₃

[ Molecular Weight ]:
324.15900

[ Exact Mass ]:
323.01200

[ PSA ]:
51.05000

[ LogP ]:
4.22690

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H400

[ Precautionary Statements ]:
P273-P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Synthetic Route

Click to get detail synthetic route

Articles

Aldehyde dedydrogenase-2 plays a beneficial role in ameliorating chronic alcohol-induced hepatic steatosis and inflammation through regulation of autophagy.

J. Hepatol. 62(3) , 647-56, (2015)

Mitochondrial aldehyde dehydrogenase (ALDH2) plays a critical role in the detoxification of the ethanol metabolite acetaldehyde. This study was designed to examine the impact of global ALDH2 overexpre...

Pharmacological activation of aldehyde dehydrogenase 2 by Alda-1 reverses alcohol-induced hepatic steatosis and cell death in mice.

J. Hepatol. 62 , 1375-81, (2015)

Effective therapies for alcoholic liver disease are currently unavailable. The present study tested the efficacy of Alda-1, a specific aldehyde dehydrogenase 2 (ALDH2) activator, in treating alcoholic...

Mitochondrial aldehyde dehydrogenase activation by Alda-1 inhibits atherosclerosis and attenuates hepatic steatosis in apolipoprotein E-knockout mice.

J. Am. Heart Assoc. 3(6) , e001329, (2014)

Mitochondrial dysfunction has been shown to play an important role in the development of atherosclerosis and nonalcoholic fatty liver disease (NAFLD). Mitochondrial aldehyde dehydrogenase (ALDH2), an ...

Propane,1,1-bis(ethylsulfonyl)-2-methyl-
trans-1,2-Dimethylcyclohexane
Cyclohexanecarboxylicacid, 1-methyl-3-oxo-, ethyl ester
2-[1-(2-hydroxy-3,5-dimethylphenyl)cyclohexyl]-4,6-dimethylphenol
3-[1-(2,5-dimethylthiophen-3-yl)octadecyl]-4-propan-2-ylideneoxolane-2,5-dione
Pyridinium, 1- (2-hydroxy[1,1:3,1-terphenyl]-5-yl)-2,4, 6-triphenyl-, perchlorate (salt)