blasticidin s hydrochloride

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Names

[ CAS No. ]:
3513-03-9

[ Name ]:
blasticidin s hydrochloride

[Synonym ]:
MFCD02091640
Blasticidine S hydrochloride
BlasticidinS,monohydrochloride (8CI)
Blasticidin S hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
772.1ºC at 760 mmHg

[ Molecular Formula ]:
C17H27ClN8O5

[ Molecular Weight ]:
458.90

[ Flash Point ]:
420.8ºC

[ Exact Mass ]:
458.17900

[ PSA ]:
215.67000

[ LogP ]:
1.05570

[ Storage condition ]:
−20°C

[ Water Solubility ]:
Soluble in water. Insoluble in organic solvents.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+: Very toxic;

[ Risk Phrases ]:
R28

[ Safety Phrases ]:
28-36/37-45

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

Articles

A rice fungicide blasticidin S efficiently binds Cu(II) ions and prevents DNA from metal-induced damage.

J. Inorg. Biochem. 127 , 73-8, (2013)

Blasticidin S is a representative of the aminoacylnucleoside class of antibiotics and it possesses fungicidal properties against the virulent fungus which causes a serious rice blast disease in Asia. ...

Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.

Proc. Natl. Acad. Sci. U. S. A. 110(30) , 12283-8, (2013)

The antibiotic blasticidin S (BlaS) is a potent inhibitor of protein synthesis in bacteria and eukaryotes. We have determined a 3.4-Å crystal structure of BlaS bound to a 70S⋅tRNA ribosome complex and...

Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: Implications for non-Hodgkin's lymphoma.

Proc. Natl. Acad. Sci. U. S. A. 103 , 13485-13490, (2006)

Human B lymphocytes and derived lines from a spectrum of B cell malignancy were studied for expression of dopaminergic pathway components and for their cytostatic response to the catecholamine and rel...


More Articles

Related Compounds

  • Blasticidin S
  • GRAMICIDIN S HYDROCHLORIDE
  • (S)-(4-Bromophenyl)(phenyl)methanamine hydrochloride
  • bis(2-chloroethyl)-propan-2-ylazanium,chloride
  • Chloropyramine hydrochloride
  • (+)-(S)-Mexiletine hydrochloride
  • methyl 4-(2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)acetamido)benzoate
  • N-(3-acetamidophenyl)-2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)acetamide
  • 2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)-N-(4-fluorobenzyl)acetamide
  • 2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)-N-((tetrahydrofuran-2-yl)methyl)acetamide
  • N-(benzo[d]thiazol-2-yl)-2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)acetamide
  • 2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
  • ethyl 2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)propanoate
  • ethyl 2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)butanoate
  • 1-(2,6-dimethylmorpholino)-2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)ethanone
  • N-(3-chlorophenyl)-2-((1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)thio)acetamide
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