2'-Hydroxy-3-phenylpropiophenone

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Names

[ CAS No. ]:
3516-95-8

[ Name ]:
2'-Hydroxy-3-phenylpropiophenone

[Synonym ]:
2'-hydroxydihydrochalcone
2-Hydroxyphenyl Phenethyl Ketone
2′-Hydroxy-3-phenylpropiophenone
1-(2-Hydroxyphenyl)-3-phenyl-1-propanone
2-Hydroxyphenyl 2-Phenylethyl Ketone
2'-HYDROXY-3',4'-DIMETHOXYACETOPHENONE
1-Propanone, 1-(2-hydroxyphenyl)-3-phenyl-
1-(2-hydroxyphenyl)-3-phenylpropan-1-one
MFCD00002221
2'-Hydroxy-3-phenylpropiophenone
EINECS 222-521-4

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
381.1±25.0 °C at 760 mmHg

[ Melting Point ]:
36-37 °C(lit.)

[ Molecular Formula ]:
C15H14O2

[ Molecular Weight ]:
226.270

[ Flash Point ]:
162.7±15.8 °C

[ Exact Mass ]:
226.099380

[ PSA ]:
37.30000

[ LogP ]:
4.13

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.600

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2'-HYDROXYCHALCONE
  • 2-Propen-1-one,1-(2-hydroxyphenyl)-3-phenyl-, (2E)-
  • 1-(2'-hydroxyphenyl)prop-2-en-1-ol
  • Phenylboronic acid
  • Ortho-Hydroxyacetophenone
  • Benzaldehyde
  • Benzyl alcohol
  • phenylene-ethylene
  • Salicylaldehyde
  • 6-(5-phenyl-1,2-oxazolidin-3-ylidene)cyclohexa-2,4-dien-1-one

DownStream

  • (R)-(+)-PROPAFENONE HYDROCHLORIDE
  • 1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone
  • UNII:ZK418W0W6U
  • 3-Benzylidenphthalide
  • (R)-Propafenone
  • (S)-Propafenone
  • 2-phenethylbenzooxazole
  • 3-phenethylbenzo[d]isoxazole
  • etafenone
  • 3-benzyl-2,3-dihydrochromen-4-one

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Antiarrhythmic activity of 2'-hydroxy-3-phenylpropiophenone derivatives. Nikolaevskii VA, et al.

Pharmaceut. Chem. J. 23(12) , 966-968, (1989)

Local anesthetic activity of derivatives of 2-hydroxy-3-phenylpropiophenone. Nikolaevskii VA, et al.

Pharmaceut. Chem. J. 21(9) , 646-647, (1987)


More Articles

Related Compounds

  • 2'-HYDROXY-3-PHENYLPROPIOPHENONE
  • 2'-HYDROXY-3-PHENYLPROPIOPHENONE
  • 2'-hydroxy-3,5'-dinitro-trans-chalcone
  • 2'-hydroxy-3,4,4'-trimethoxy-3'-methyl-trans-chalcone
  • 2'-Hydroxy-3,4,4',6'-tetramethoxychalcone
  • 2'-hydroxy-3,4,3',4',5',6'-hexamethoxychalcone