N-naphthalen-1-yl-4,5-dihydro-1,3-thiazol-2-amine

Names

[ CAS No. ]:
35160-17-9

[ Name ]:
N-naphthalen-1-yl-4,5-dihydro-1,3-thiazol-2-amine

[Synonym ]:
2-Thiazolamine,4,5-dihydro-N-1-naphthalenyl
2-Thiazoline,2-(1-naphthylamino)
(4,5-Dihydro-thiazol-2-yl)-[1]naphthyl-amin
2-(1-Naphthylamino)-2-thiazoline
(4,5-dihydro-thiazol-2-yl)-naphthalen-1-yl-amine

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
405ºC at 760 mmHg

[ Molecular Formula ]:
C13H12N2S

[ Molecular Weight ]:
228.31300

[ Flash Point ]:
198.7ºC

[ Exact Mass ]:
228.07200

[ PSA ]:
49.69000

[ LogP ]:
2.86310

[ Index of Refraction ]:
1.687

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ6646100
CHEMICAL NAME :
2-Thiazoline, 2-(1-naphthylamino)-
CAS REGISTRY NUMBER :
35160-17-9
BEILSTEIN REFERENCE NO. :
0163062
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H12-N2-S
MOLECULAR WEIGHT :
228.33
WISWESSER LINE NOTATION :
L66J BM- BT5N CS AUTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 14,553,1979

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethanolamine-O-sulfate
  • 1-naphthyl isothiocyanate
  • 1-(2-hydroxyethyl)-3-naphthalen-1-ylthiourea
  • aziridine-1-carbothioic acid-[1]naphthylamide

DownStream

Related Compounds

  • N-naphthalen-1-yl-4,5-dihydro-1,3-oxazol-2-amine
  • N-(1-methylindazol-4-yl)-4,5-dihydro-1,3-thiazol-2-amine
  • N-(2,3-dihydro-1H-inden-1-yl)-4,5-dihydro-1,3-thiazol-2-amine
  • 2-Thiazolamine,4,5-dihydro-N-(2-methyl-2-propenyl)-(9CI)
  • N-[[10-[2-(4-methylpiperazin-1-yl)ethyl]acridin-9-ylidene]amino]-4,5-dihydro-1,3-thiazol-2-amine
  • N-decalin-1-yl-4,5-dihydro-1,3-oxazol-2-amine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-(5-Chloro-2-fluorophenyl)-3-propanoylpiperidin-2-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2,2,2-Trichloro-N-methylethanimidoyl isocyanate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine