(10α,23E)-2β,16α-Bis(acetyloxy)-20,25-dihydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione

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Names

[ CAS No. ]:
3520-11-4

[ Name ]:
(10α,23E)-2β,16α-Bis(acetyloxy)-20,25-dihydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione

[Synonym ]:
2,16-Di-O-acetylcucurbitacin R
2,16-Di-O-acetylcucurbitacin D
Diacetyl-2,16 cucurbitacine (D)

Chemical & Physical Properties

[ Molecular Formula ]:
C34H48O9

[ Molecular Weight ]:
600.74000

[ Exact Mass ]:
600.33000

[ PSA ]:
144.27000

[ LogP ]:
4.07010

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC6183000
CHEMICAL NAME :
19-Nor-9-beta,10-alpha-lanosta-5,23-diene-3,11,22-tri one, 9-methyl-2-beta,16-alpha,20,25- tetrahydroxy-, 2-beta,16-alpha-diacetate
CAS REGISTRY NUMBER :
3520-11-4
BEILSTEIN REFERENCE NO. :
3190816
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C34-H48-O9
MOLECULAR WEIGHT :
600.82
WISWESSER LINE NOTATION :
L E5 B666 CV OV LUTJ B1 E1 FXQ1&V1U1XQ1&1 GOV1 I1 N1 N1 POV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 4,459,1969

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethanoic anhydride

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(3-Methylbutoxy)ethanesulfonamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 3-(Bromomethyl)-1-ethoxy-5-methylhexane
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine