Rifampicin AF 013

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Names

[ CAS No. ]:
35225-13-9

[ Name ]:
Rifampicin AF 013

[Synonym ]:
3-Formylrifamycin SV O-octyloxime
AF 013
3-Formylrifamycin SV O-n-octyloxim
3-Formylrifamycin SV O-n-octyloxime
Rifamycin AF 013

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Molecular Formula ]:
C46H64N2O13

[ Molecular Weight ]:
853.00600

[ Exact Mass ]:
852.44100

[ PSA ]:
222.90000

[ LogP ]:
7.60310

[ Index of Refraction ]:
1.592

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1863000
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 3-formyl-5,6,9, 17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-he ptamethyl-, 21-acetate, O-octyloxime
CAS REGISTRY NUMBER :
35225-13-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C46-H64-N2-O13
MOLECULAR WEIGHT :
853.12
WISWESSER LINE NOTATION :
T C6 B65-24- A D E 2BC G& AV LO NO F&VM OU B&U D&U MH&&&TJ DQ E1UNO8 GQ IQ J1 M1 QO1 R1 SOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
88 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,396,1974

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • O-octyl-hydroxylamine
  • 3-Formyl Rifamycin

DownStream

Related Compounds

  • Rifamycin,3-[(1-piperazinylimino)methyl]-
  • Rifampicin
  • Rifampicin-d3
  • RIFAMPICIN N-OXIDE
  • Rifampicin N-4'-Oxide
  • RIFAMPICIN
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  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
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  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 2-{[3-ethyl-7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]thio}-N-(4-fluorobenzyl)acetamide