RGX-202

Suppliers

Names

[ CAS No. ]:
353-09-3

[ Name ]:
RGX-202

[Synonym ]:
EINECS 206-530-0
β-Alanine, N-(aminoiminomethyl)-
3-(diaminomethylideneamino)propanoic acid
n-carbamimidoyl-|A-alanine
beta-Guanidinopropionic acid
3-Guanidinopropanoate
3-carbamimidamidopropanoic acid
N-Carbamimidoyl-β-alanine
N-(Aminomethyl)-β-alanine
MFCD00045939
Guanidinopropionic acid
3-Guanidinopropionic Acid
β-Guanidinopropionic acid
b-Guanidinopropionate
3-Guanidinopropanoic acid
3-guanidinepropionic acid

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
299.1±42.0 °C at 760 mmHg

[ Melting Point ]:
222 °C (dec.)(lit.)

[ Molecular Formula ]:
C4H9N3O2

[ Molecular Weight ]:
131.133

[ Flash Point ]:
134.7±27.9 °C

[ Exact Mass ]:
131.069473

[ PSA ]:
99.20000

[ LogP ]:
-1.68

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.575

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AY3157500

[ HS Code ]:
2925290090

Synthetic Route

Precursor & DownStream

Precursor

  • beta-Alanine
  • Aminoiminomethanesulfonic acid
  • Thiourea dioxide
  • gpal
  • 2-methyl-2-thiopseudourea sulfate
  • Methyl carbamimidate
  • Cyanamide

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

Eur. J. Pharmacol. 519(1-2) , 43-7, (2005)

Searching for potent and subtype selective parent structures of the murine gamma-aminobutyric acid (GABA) transporter subtypes mGAT3 and mGAT4 a series of amino acids was characterised in a uniform [3...

Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...

Accumulation of methylguanidine and changes in guanidino compound levels in plasma, urine, and kidneys of furosemide-treated rats.

Metab. Clin. Exp. 57(6) , 802-10, (2008)

Antidiuresis and renal diseases alter the levels of guanidino compounds (GCs) in various tissues. Therefore, we hypothesized that diuresis could also disturb GC metabolism, storage, and elimination. I...


More Articles


Related Compounds

  • RGX-104
  • RGX-104 free Acid
  • thallium-202
  • AP-202
  • Antibiotic-202
  • SDZ-202 791 R(-)
  • tert-Butyl 4-((5-iodonaphthalen-1-yl)sulfonyl)-1,4-diazepane-1-carboxylate
  • tert-Butyl ((1R)-2-ethynylcyclohexyl)carbamate
  • 3-Bromo-4-(difluoromethyl)-6-methylpyridin-2-amine
  • 2-Chloro-3-(difluoromethyl)-5-nitro-6-(trifluoromethyl)pyridine
  • 5-(Difluoromethyl)-3-methyl-4-nitropyridin-2-amine
  • tert-Butyl ((1R,2R)-2-((4-(trifluoromethyl)benzyl)oxy)cyclohexyl)carbamate
  • tert-Butyl (3-bromopyrazine-2-carbonyl)(tert-butoxy)carbamate
  • tert-butyl N-[1-(4-bromophenyl)-1-hydroxypropan-2-yl]carbamate
  • 1,1-Diisopropoxy-3,3-dimethoxycyclobutane
  • 4-Bromo-2-(((tert-butoxycarbonyl)amino)methyl)benzoic acid
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