GELSEMINE HYDROCHLORIDE

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Names

[ CAS No. ]:
35306-33-3

[ Name ]:
GELSEMINE HYDROCHLORIDE

[Synonym ]:
Gelsemine,hydrochloride
Gelsemin,Hydrochlorid
Gelsemine,monohydrochloride
EINECS 252-504-7
Gelsemine HCl

Chemical & Physical Properties

[ Boiling Point ]:
493.4ºC at 760mmHg

[ Melting Point ]:
>300ºC

[ Molecular Formula ]:
C20H23ClN2O2

[ Molecular Weight ]:
358.86200

[ Flash Point ]:
252.2ºC

[ Exact Mass ]:
358.14500

[ PSA ]:
41.57000

[ LogP ]:
2.90550

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LX9150000
CHEMICAL NAME :
Gelsemine, monohydrochloride
CAS REGISTRY NUMBER :
35306-33-3
LAST UPDATED :
199203
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H22-N2-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
DUSA** "Dispensatory of the United States of America," 24th ed., Osol, A. and G.E. Farrar, Philadelphia, J.B. Lippincott Co., 1947 Volume(issue)/page/year: 24,497,1947
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
ZEBLA3 Zeitschrift fuer Biologie. (Munich, Fed. Rep. Ger.) V.1-116, 1865-1971. Discontinued. Volume(issue)/page/year: 99,446,1939

Related Compounds

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