1-(2-Methoxyphenyl)piperazine

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Names

[ CAS No. ]:
35386-24-4

[ Name ]:
1-(2-Methoxyphenyl)piperazine

[Synonym ]:
Piperazine, 1-(o-methoxyphenyl)-
Piperazine, 1-(2-methoxyphenyl)-
2-MPP
o-Methoxyphenylpiperazine
MFCD00005958
1-(2-Methoxyphenyl)piperazine
2-(1-Piperazinyl)anisole
N-(o-Methoxyphenyl)piperazine
EINECS 252-537-7
1-(O-METHOXYPHENYL)PIPERAZINE
1-(O-ANISYL)PIPERAZINE
piperazine, 1-(2-methyloxyphenyl)-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
379.9±0.0 °C at 760 mmHg

[ Melting Point ]:
35-40 °C(lit.)

[ Molecular Formula ]:
C11H16N2O

[ Molecular Weight ]:
192.258

[ Flash Point ]:
154.0±23.7 °C

[ Exact Mass ]:
192.126266

[ PSA ]:
24.50000

[ LogP ]:
1.13

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.534

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45-S28A

[ RIDADR ]:
UN 3263 8/PG 3

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperazine
  • bromoanisole
  • Bis(2-Chloroethyl)amine hydrochloride
  • 2-Anisidine
  • 2-Chloroanisole
  • piperazinium chloride
  • 1-(2-Methoxyphenyl)piperazine hydrochloride
  • 1-(2-methoxyphenyl)piperazine-2,6-dione
  • Tri-o-tolylphosphine

DownStream

  • 1-(2-methoxyphenyl)-4-[(2-phenyl-1H-imidazol-5-yl)methyl]piperazine
  • 4-(2-Methoxyphenyl)-N-2-pyridinyl-1-piperazineacetamide
  • 2-[4-(2-METHOXYPHENYL)PIPERAZINO]ETHANETHIOAMIDE
  • 2-(4-BENZYLPIPERAZIN-1-YL)METHOXYBENZENE
  • 4-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-BUTYLAMINE
  • 2-chloro-1-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone,hydrochloride
  • 1-(2-HYDROXYMETHYL-PHENYL)-PIPERIDINE-3-CARBOXYLICACIDETHYLESTER
  • Naftopidil
  • S-(-)-Naftopidil
  • R-(+)-Naftopidil

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Development of a novel derivatization reagent for the sampling and analysis of total isocyanate group in air and comparison of its performance with that of several established reagents.

Am. Ind. Hyg. Assoc. J. 57(10) , 905-13, (1996)

Analytical reference standards generally are not available for non-monomeric isocyanate species, making accurate identification and quantitation by high-performance liquid chromatography (HPLC) diffic...

Comparison of hollow fiber liquid-phase microextraction and ultrasound-assisted low-density solvent dispersive liquid-liquid microextraction for the determination of drugs of abuse in biological samples by gas chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 989 , 46-53, (2015)

Two microextraction techniques based on hollow fiber liquid-phase microextraction (HF-LPME) and ultrasound-assisted low-density solvent dispersive liquid-liquid microextraction (UA-LDS-DLLME) had been...

Preparation and biodistribution of 1-((2-methoxyphenyl) piperazine)ferrocenecarboxamide labeled with technetium-99m as a potential brain receptor imaging agent.

Eur. J. Med. Chem. 97 , 280-8, (2015)

The goal of this study is to develop a novel brain receptor imaging agent. This study reports the synthesis, characterization and the biological evaluation of 1-((2-methoxyphenyl) piperazine)ferrocene...


More Articles

Related Compounds

  • 1-(2-methoxyphenyl)piperazine-2,6-dione
  • 1-(2-METHOXYPHENYL)PIPERAZINE CARBONATE
  • 1-(2-Methoxyphenyl)Piperazine Hydrobromide
  • 1-(2-Methoxyphenyl)piperazine hydrochloride
  • 1-(2-Methoxyphenyl)piperazine hydrochloride
  • carbonic acid,1-(2-methoxyphenyl)piperazine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • Methyl 3-methoxy-5-(4-methoxyphenyl)benzoate
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-(3-hydroxy-3-(naphthalen-1-yl)propyl)thiophene-2-sulfonamide
  • ethyl 2-(2-(2-(cyclopropanecarboxamido)-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)acetamido)benzoate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde