Benzenamine,2-methoxy-4-(2-phenyldiazenyl)-

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Names

[ Name ]:
Benzenamine,2-methoxy-4-(2-phenyldiazenyl)-

[Synonym ]:
2-methoxy-4-phenylazo-aniline
4-Amino-3-methoxyazobenzene
3-Methoxy-4-amino-azobenzol
Azobenzene,4-amino-3-methoxy
3-Methoxy-4-aminoazobenzene
5-Benzolazo-2-amino-phenol-methylaether
Benzenamine,2-methoxy-4-(phenylazo)
4-(Phenylazo)-o-anisidine
Aniline,2-methoxy-4-phenylazo
o-ANISIDINE,4-(PHENYLAZO)
Benzol-azo-o-anisidin
5-Benzolazo-2-amino-anisol
4-Amino-3-methoxy-azobenzol

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
398.8ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₁₃N₃O

[ Molecular Weight ]:
227.26200

[ Flash Point ]:
195ºC

[ Exact Mass ]:
227.10600

[ PSA ]:
59.97000

[ LogP ]:
4.27400

[ Index of Refraction ]:
1.592

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ7350000

CHEMICAL NAME :: o-Anisidine, 4-(phenylazo)-

CAS REGISTRY NUMBER :: 3544-23-8

BEILSTEIN REFERENCE NO. :: 1842457

LAST UPDATED :: 199612

DATA ITEMS CITED :: 25

MOLECULAR FORMULA :: C13-H13-N3-O

MOLECULAR WEIGHT :: 227.29

WISWESSER LINE NOTATION :: 1OR BZ ENUNR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7950 mg/kg/34W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1490 mg/kg/93W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 gm/kg/56W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18 gm/kg/66W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19 gm/kg/49W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8 gm/kg/22W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 gm/kg/56W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40320 mg/kg/56W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30400 mg/kg/56W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 250 umol/L

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 58,199,1991

Safety Information

[ HS Code ]:
2927000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

benzenediazonium
Benzenediazonium chloride
2-Anisidine

DownStream

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds

Benzenamine, 2-methoxy-4-(2-methoxyethoxy)- (9CI)
2-methoxy-4-[(2-methylimidazol-1-yl)methyl]aniline
2-methoxy-4-[2-(4-methylpiperazin-1-yl)ethyl]aniline
4-[(4-nitrophenyl)azo]-o-anisidine
2-Methoxy-4-(o-methoxyphenylazo)aniline
Benzenamine,2-methoxy-4-nitroso-
3-[4-nitro-3-(3,3,3-trifluoropropoxy)-1H-pyrazol-1-yl]propan-1-amine
2-[4-nitro-3-(3,3,3-trifluoropropoxy)-1H-pyrazol-1-yl]ethanamine
2-[4-nitro-3-(3,3,3-trifluoropropoxy)-1H-pyrazol-1-yl]butanoic acid
2-methyl-2-[4-nitro-3-(3,3,3-trifluoropropoxy)-1H-pyrazol-1-yl]propanoic acid
3-[4-nitro-3-(3,3,3-trifluoropropoxy)-1H-pyrazol-1-yl]butanoic acid
2-methyl-3-[4-nitro-3-(3,3,3-trifluoropropoxy)-1H-pyrazol-1-yl]propanoic acid
[4-nitro-3-(2,2,2-trifluoroethoxy)-1H-pyrazol-1-yl]acetic acid
3-[4-nitro-3-(2,2,2-trifluoroethoxy)-1H-pyrazol-1-yl]propanoic acid
3-[4-nitro-3-(2,2,2-trifluoroethoxy)-1H-pyrazol-1-yl]propan-1-amine
2-[4-nitro-3-(2,2,2-trifluoroethoxy)-1H-pyrazol-1-yl]ethanamine

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