Cyamemazine

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Names

[ CAS No. ]:
3546-03-0

[ Name ]:
Cyamemazine

[Synonym ]:
Kyamepromazin
Kyamepromazine
10H-Phenothiazine-2-carbonitrile, 10-[3-(dimethylamino)-2-methylpropyl]-
7204 R.E.
Ciamatil
Cyamemazine
10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile
2-Cyano-10-(3-dimethylamino-2-methylpropyl)phenothiazine
Tercian
10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
479.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H21N3S

[ Molecular Weight ]:
323.455

[ Flash Point ]:
243.5±28.7 °C

[ Exact Mass ]:
323.145630

[ PSA ]:
55.57000

[ LogP ]:
4.62

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.655

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN6950000
CHEMICAL NAME :
Phenothiazine-2-carbonitrile, 10-(3-(dimethylamino)-2-methylpropyl)-
CAS REGISTRY NUMBER :
3546-03-0
BEILSTEIN REFERENCE NO. :
0093261
LAST UPDATED :
199703
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H21-N3-S
MOLECULAR WEIGHT :
323.49
WISWESSER LINE NOTATION :
T C666 BN ISJ B1Y1&1N1&1 ECN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,573,1982
TYPE OF TEST :
Rinsed with water
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,573,1982 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
107 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JATOD3 Journal of Analytical Toxicology. (Preston Pub. Inc., POB 48312, Niles, IL 60648) V.1- 1977- Volume(issue)/page/year: 17,386,1993

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2934300000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-carboxyphenothiazine
  • 2-Cyano-phenothiazine
  • 2-Chlorophenothiazine
  • 3-chloro-2-methylpropyl(dimethyl)amine

DownStream

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • Cyamemazine-d6
  • Cyamemazine maleate
  • cyamemazine N-oxide
  • Cyamemazine tartrate
  • N-Demethylcyamemazine