SC-514

Names

[ Name ]:
SC-514

[Synonym ]:
4-Amino-2,3'-bithiophene-5-carboxamide
[2,3'-Bithiophene]-5-carboxamide, 4-amino-
4-Amino-[2,3"]bithiophenyl-5-carboxylic acid amide
SC-514
IKK-2 Inhibitor
GK 01140

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
399.2±42.0 °C at 760 mmHg

[ Melting Point ]:
209-211°C

[ Molecular Formula ]:
C₉H₈N₂OS₂

[ Molecular Weight ]:
224.303

[ Flash Point ]:
195.2±27.9 °C

[ Exact Mass ]:
224.007797

[ PSA ]:
125.59000

[ LogP ]:
1.52

[ Appearance of Characters ]:
white to light brown

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.715

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: soluble10mg/mL, clear

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

Precursor & DownStream

Precursor

Methyl 3-amino-5-(thien-3-yl)thiophene-2-carboxylate
4-amino-[2,3'-bithiophene]-5-carboxylic acid

DownStream

Articles

Methylprednisolone attenuates lipopolysaccharide-induced Fractalkine expression in kidney of Lupus-prone MRL/lpr mice through the NF-kappaB pathway.

BMC Nephrol. 16 , 148, (2015)

Fractalkine (FKN) is involved in the occurrence and development of human lupus nephritis. It is known to be upregulated by lipopolysaccharide (LPS) as a stimulus in vivo. MRL/lpr mice have been used a...

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