Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

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Names

[ CAS No. ]:
35511-14-9

[ Name ]:
Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide

[Synonym ]:
methyl 4-hydroxy-1,1-dioxo-2H-1λ<sup>6</sup>,2-benzothiazine-3-carboxylate

Chemical & Physical Properties

[ Density]:
1.568g/cm3

[ Boiling Point ]:
447ºC at 760mmHg

[ Melting Point ]:
168-170ºC

[ Molecular Formula ]:
C10H9NO5S

[ Molecular Weight ]:
255.24700

[ Flash Point ]:
224.2ºC

[ Exact Mass ]:
255.02000

[ PSA ]:
101.08000

[ LogP ]:
1.78770

[ Index of Refraction ]:
1.639

Safety Information

[ HS Code ]:
2934991000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
  • Sodium Saccharin
  • o-(N-Carboxamidomethylsulfamyl)benzoic Acid Methyl Ester
  • Saccharin
  • (1,1,3-trioxo-1,3-dihydro-1λ6-benzo[d]isothiazol-2-yl)-acetic acid tert-butyl ester
  • Sodium Methylate
  • 2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-6-((TRIMETHYLSILYL)ETHYNYL)FURO[3,2-B]PYRIDINE
  • propan-2-yl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
  • phenyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetate
  • Sodium ethoxide

DownStream

  • Sudoxicam
  • Methyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide
  • Piroxicam
  • Methyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide-d3
  • Isoxicam
  • Meloxicam
  • 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide
  • 4-methyl-1-naphthalen-1-ylsulfonylpiperidine

Customs

[ HS Code ]: 2934991000

[ Summary ]:
2934991000. sultones and sultams. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Tert-butyl 2-{[5-(2-methoxy-2-oxoethyl)-2-methyl-3-sulfanylphenyl]methoxy}acetate
  • (3-Formyl-5-iodo-4-methylphenyl)methanesulfonyl fluoride
  • 3-{[2-(Tert-butoxy)-2-oxoethoxy]methyl}-5-iodo-2,4,6-trimethylbenzoic acid
  • Tert-butyl 4-{[2,4,6-trimethyl-3-(piperazin-1-yl)-5-sulfanylphenyl]methyl}piperazine-1-carboxylate
  • Tert-butyl 4-{2,4,6-trimethyl-3-[(piperazin-1-yl)methyl]-5-sulfanylphenyl}piperazine-1-carboxylate
  • Tert-butyl 4-{3-[(tert-butoxy)carbonyl]-2,4,6-trimethyl-5-sulfanylphenyl}piperazine-1-carboxylate
  • {3-Iodo-2,4,6-trimethyl-5-[2-(trimethylsilyl)ethynyl]phenyl}methanesulfonyl fluoride
  • (9H-fluoren-9-yl)methyl N-[(3-amino-5-ethynyl-2-methylphenyl)methyl]carbamate
  • (9H-fluoren-9-yl)methyl N-[(5-amino-3-ethynyl-2-methylphenyl)methyl]carbamate
  • (9H-fluoren-9-yl)methyl N-[(3-amino-5-ethynyl-4-methylphenyl)methyl]carbamate
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