Azamethiphos

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Names

[ CAS No. ]:
35575-96-3

[ Name ]:
Azamethiphos

[Synonym ]:
azametifos
EINECS 252-626-0
Alfracron
S-[(6-chloro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate
S-[(6-Chloro-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate
MFCD00867611
S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-Dimethyl Phosphorothioate
snip
ALFACRON
Azamethiphos
S-[(6-Chlor-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl]-O,O-dimethylthiophosphat
Salmosan
Phosphorothioic acid, S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl ester
S-6-Chloro-2,3-dihydro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3-ylmethyl O,O-Dimethyl Phosphorothioate

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
428.8±55.0 °C at 760 mmHg

[ Melting Point ]:
88-93°C

[ Molecular Formula ]:
C9H10ClN2O5PS

[ Molecular Weight ]:
324.678

[ Flash Point ]:
213.1±31.5 °C

[ Exact Mass ]:
323.973663

[ PSA ]:
118.67000

[ LogP ]:
0.82

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.589

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TE8070000
CHEMICAL NAME :
Phosphorothioic acid, S-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2H)-yl)meth yl) O,O-dimethyl ester
CAS REGISTRY NUMBER :
35575-96-3
LAST UPDATED :
199710
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H10-Cl-N2-O5-P-S
MOLECULAR WEIGHT :
324.69
WISWESSER LINE NOTATION :
T56 BOVN FNJ D1SPO&O1&O1 HG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,44,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,44,1991

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36

[ Safety Phrases ]:
S26-S36/37-S24/25-S23

[ RIDADR ]:
UN 1593 6.1/PG 3

[ RTECS ]:
TE8070000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Chlorooxazolo[4,5-b]pyridin-2(3H)-one
  • 6-chloro-3-(hydroxymethyl)-[1,3]oxazolo[4,5-b]pyridin-2-one
  • 2-Amino-3-pyridinol
  • 2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one
  • 6-chloro-3-chloromethyl-3H-oxazolo[4,5-b]pyridin-2-one
  • ammonium O,O-dimethyl thiophosphate

DownStream

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Environ. Pollut. 152(2) , 342-50, (2008)

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Related Compounds

  • Azamethiphos-d6
  • N-(2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-1-tosylpiperidine-4-carboxamide
  • 7-methoxy-N-(2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)benzofuran-2-carboxamide
  • N-(2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)benzo[d][1,3]dioxole-5-carboxamide
  • 1,3-dimethyl-N-{2-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazol-3-yl}-1H-pyrazole-5-carboxamide
  • 2-(4-methoxy-3-methylphenyl)-N-(2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)acetamide
  • 3-methyl-N-(2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)isoxazole-5-carboxamide
  • N-(2-(4-methylpiperazin-1-yl)benzo[d]thiazol-6-yl)-5-nitrothiophene-2-carboxamide
  • 2-(4-chlorophenoxy)-N-(2-(4-methylpiperazin-1-yl)benzo[d]thiazol-6-yl)acetamide
  • N~6~-(1,3-benzodioxol-5-ylmethyl)-N~4~-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
  • N-(4-fluorophenyl)-6-[4-(4-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine