(1-ethylpiperidin-3-yl) 2-hydroxy-2,2-diphenylacetate

Names

[ CAS No. ]:
3567-12-2

[ Name ]:
(1-ethylpiperidin-3-yl) 2-hydroxy-2,2-diphenylacetate

[Synonym ]:
Ditran JB 318
Benzilic acid,1-ethyl-3-piperidyl ester
N-ETHYL-3-PIPERIDYL BENZILATE
DEA No. 7482
1-Ethyl-3-piperidyl benzilate

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
429.5ºC at 760 mmHg

[ Molecular Formula ]:
C21H25NO3

[ Molecular Weight ]:
339.42800

[ Flash Point ]:
213.6ºC

[ Exact Mass ]:
339.18300

[ PSA ]:
49.77000

[ LogP ]:
2.88790

[ Index of Refraction ]:
1.602

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD3505000
CHEMICAL NAME :
Benzilic acid, 1-ethyl-3-piperidyl ester
CAS REGISTRY NUMBER :
3567-12-2
BEILSTEIN REFERENCE NO. :
0309916
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C21-H25-N-O3
MOLECULAR WEIGHT :
339.47
WISWESSER LINE NOTATION :
T6MTJ COVXQR&R& C2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
34 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
19 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Chloro-1-ethylpiperidine
  • Benzilic acid

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2S)-1-benzyl-2,5,5-trimethyl-1,4-diazepane
  • [2-fluoro-5-methyl-4-(4-methylthiazol-5-yl)phenyl]methanamine
  • 4-Pyridazinemethanol, 3-chloro-6-methoxy-
  • 1-Piperidinecarboxylic acid, 4-[3-(aminomethyl)-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester
  • 5-Chloro-2-fluoro-4-(trifluoromethyl)benzamide
  • 1H-Indazole, 5-bromo-7-chloro-1-(tetrahydro-2H-pyran-2-yl)-
  • N-(2-(Aminomethyl)pyridin-4-yl)methanesulfonamide
  • Ethyl 2-(2-bromoethoxy)-2-(4-(trifluoromethoxy)phenyl)acetate
  • 4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-6-one
  • 6-(Methoxymethoxy)-1,3-dioxaindane-5-sulfonyl chloride