(1-ethylpiperidin-3-yl) 2-hydroxy-2,2-diphenylacetate

Names

[ Name ]:
(1-ethylpiperidin-3-yl) 2-hydroxy-2,2-diphenylacetate

[Synonym ]:
Ditran JB 318
Benzilic acid,1-ethyl-3-piperidyl ester
N-ETHYL-3-PIPERIDYL BENZILATE
DEA No. 7482
1-Ethyl-3-piperidyl benzilate

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
429.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₅NO₃

[ Molecular Weight ]:
339.42800

[ Flash Point ]:
213.6ºC

[ Exact Mass ]:
339.18300

[ PSA ]:
49.77000

[ LogP ]:
2.88790

[ Index of Refraction ]:
1.602

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD3505000

CHEMICAL NAME :: Benzilic acid, 1-ethyl-3-piperidyl ester

CAS REGISTRY NUMBER :: 3567-12-2

BEILSTEIN REFERENCE NO. :: 0309916

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H25-N-O3

MOLECULAR WEIGHT :: 339.47

WISWESSER LINE NOTATION :: T6MTJ COVXQR&R& C2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 19 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-Chloro-1-ethylpiperidine
Benzilic acid

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

(4-Fluorophenyl)[4-(3-hydroxyphenyl)-1-piperidinyl]methanone
2-(3-Methoxyprop-1-yn-1-yl)-4-methylpyridine
[1-(Propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-yl] 2-methylpropanoate
(6-Bromo-4-hexyn-1-yl)benzene
Desferrioxamine D1
Dimethyl 8-bromoquinoline-2,4-dicarboxylate
N-(tert-Butoxycarbonyl)-4-(methoxycarbonyl)phenylalanine
3-(Pyridin-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-amine
1-(2-Chlorophenyl)-N-(11C)methyl-N-((1R))-methylpropyl)isoquinoline-3-carboxamide
1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-1-methyl-5-phenyl-, (4a-alpha,5-beta,9b-alpha)-

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.