N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-toluenesulfonamide

Suppliers

Names

[ CAS No. ]:
3572-41-6

[ Name ]:
N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-p-toluenesulfonamide

[Synonym ]:
5-p-Tolylsulfonylamino-2-isobutyl-1,3,4-thiadiazol
2-p-Methylbenzenesulfonamido-5-isobutyl-1,3,4-thiadiazole
5-p-Toluolsulfonylamino-2-isobutyl-1,3,4-thiadiazol
FWH 106

Chemical & Physical Properties

[ Density]:
1.314g/cm3

[ Boiling Point ]:
464.7ºC at 760 mmHg

[ Molecular Formula ]:
C13H17N3O2S2

[ Molecular Weight ]:
311.42300

[ Flash Point ]:
234.8ºC

[ Exact Mass ]:
311.07600

[ PSA ]:
108.57000

[ LogP ]:
3.99960

[ Index of Refraction ]:
1.597

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT5830000
CHEMICAL NAME :
p-Toluenesulfonamide, N-(5-isobutyl-1,3,4-thiadiazol-2-yl)-
CAS REGISTRY NUMBER :
3572-41-6
BEILSTEIN REFERENCE NO. :
0271816
LAST UPDATED :
199707
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H17-N3-O2-S2
MOLECULAR WEIGHT :
311.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2400 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1650 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Methylbutanoic acid
  • Thiosemicarbazide
  • Tosyl chloride

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

  • 4-(2-Bromo-3-methylphenyl)-2-(difluoromethyl)pyridine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • benzyl N-{6-hydroxy-2H-pyrazolo[3,4-b]pyridin-3-yl}carbamate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine