moxastine

Suppliers

Names

[ CAS No. ]:
3572-74-5

[ Name ]:
moxastine

[Synonym ]:
Spofa 325
Theadrylettae
Mephenhydramine
Mephenhydraminum
Moxastine
Therdryl
Moxastin

Chemical & Physical Properties

[ Density]:
1.013g/cm3

[ Boiling Point ]:
357.5ºC at 760mmHg

[ Molecular Formula ]:
C18H23NO

[ Molecular Weight ]:
269.38100

[ Flash Point ]:
105.5ºC

[ Exact Mass ]:
269.17800

[ PSA ]:
12.47000

[ LogP ]:
3.52830

[ Index of Refraction ]:
1.542

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR6715000
CHEMICAL NAME :
Ethylamine, 2-(1,1-diphenylethoxy)-N,N-dimethyl-
CAS REGISTRY NUMBER :
3572-74-5
BEILSTEIN REFERENCE NO. :
1981628
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H23-N-O
MOLECULAR WEIGHT :
269.42
WISWESSER LINE NOTATION :
1XR&R&O2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
95 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 2,323,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
43 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,189,1954 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2100 mg/kg/6W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,531,1961

Safety Information

[ HS Code ]:
2922199090

Synthetic Route

Precursor & DownStream

Precursor

  • 1,1-DIPHENYLETHANOL
  • (2-Chloroethyl)dimethylamine hydrochloride

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • Moxastine
  • Moxastine hydrochloride