2,5-Difluorobenzoyl chloride

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Names

[ Name ]:
2,5-Difluorobenzoyl chloride

[Synonym ]:
Benzoyl chloride, 2,5-difluoro-
EINECS 252-701-8
difluorobenzoic acid chloride
MFCD00009929
2,5-diflurobenzoyl chloride
GVR BF EF
2,5-Difluorobenzoyl chloride
2,5-difluoro-benzoyl chloride
Benzoyl chloride,2,5-difluoro
2,4-DIFLUOROBENZOYLACETONITRILE
2,5-diflourobenzoyl chloride

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
183.8±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₃ClF₂O

[ Molecular Weight ]:
176.548

[ Flash Point ]:
59.4±0.0 °C

[ Exact Mass ]:
175.984055

[ PSA ]:
17.07000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.8±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.499

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S45-S36/37/39-S25-S26

[ RIDADR ]:
3265

[ WGK Germany ]:
3.0

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

2,5-difluoro-N-methoxy-N-methylbenzamide
3,6-Difluorophthalic anhydride
3,6-Difluorophthalic acid
N,N-Diethyl-2,5-difluorobenzamide
N,N-DIETHYL-3,6-DIFLUOROPHTHALAMIC ACID
1,4-Difluoro-5,8-dihydroxyanthraquinone
2-[(2-benzoylphenyl)sulfanylmethyl]-2-ethylhexanal
9,10-Anthracenedione,1,4-bis[[2-(dimethylamino)ethyl]amino]-

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen.

Cell Cycle 7(21) , 3417-27, (2008)

A robust p53 cell-based assay that exploits p53's function as a transcription factor was used to screen a small molecule library and identify bioactive small molecules with potential antitumor activit...

Synthesis, determination of absolute configuration, and biological evaluation of spiro-fused thiadiazoline inhibitors of kinesin spindle protein (KSP). Angeles AR, et al.

Tetrahedron Lett. 51(48) , 6236-39, (2010)