4,5-Dimethylthiazole

Suppliers

Names

[ Name ]:
4,5-Dimethylthiazole

[Synonym ]:
EINECS 222-703-3
FEMA No. 3274
4,5-Dimethyl-thiazol
4-27-00-00986 (Beilstein Handbook Reference)
MFCD00005336
4,5-Dimethyl-1,3-thiazole
Thiazole,4,5-dimethyl
4,5-Dimethylthiazole
Thiazole, 4,5-dimethyl-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
158.1±9.0 °C at 760 mmHg

[ Melting Point ]:
83-84ºC

[ Molecular Formula ]:
C₅H₇NS

[ Molecular Weight ]:
113.181

[ Flash Point ]:
51.1±0.0 °C

[ Exact Mass ]:
113.029922

[ PSA ]:
41.13000

[ LogP ]:
1.36

[ Vapour Pressure ]:
3.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.531

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ4380000

CHEMICAL NAME :: Thiazole, 4,5-dimethyl-

CAS REGISTRY NUMBER :: 3581-91-7

BEILSTEIN REFERENCE NO. :: 0105694

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H7-N-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 960 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,95,1990

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R22;R36/37/38

[ Safety Phrases ]:
S16-S26-S39-S37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XJ4380000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(Z)-Methanimidic acid
3-Bromo-2-butanone
N-methylimine of methyl ethyl ketone
4,5-DIMETHYL-1,3-THIAZOL-2-AMINE
4,5-Dimethyl-thiazole-2-thiol
4,5-dimethyl-1,3-oxazole
Formamide, N-(1-methyl-2-oxopropyl)- (9CI)
Thioformamide
3-Chloro-2-butanone

DownStream

4-(chloromethyl)-5-methyl-1,3-thiazole,hydrochloride
Thiazole,4-(chloromethyl)-5-methyl-
5-(Dibromomethyl)-4-methyl-1,3-thiazole
5-Formyl-4-methylthiazole
4,5-Dimethyl-1,3-thiazole-2-carboxylic acid
2-Acetyl-4,5-dimethylthiazole
5-chloromethyl-4-Methyl-1,3-thiazole
3-benzyl-4,5-dimethyl-1,3-thiazol-3-ium,chloride
2-Bromo-4,5-dimethylthiazole
4,5-Dimethylthiazole-2-carbaldehyde

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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