1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin

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Names

[ CAS No. ]:
35822-46-9

[ Name ]:
1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin

[Synonym ]:
PCDD 73
1,2,3,4,6,7,8-Heptachlorodibenzo-para-dioxin
1,2,3,4,6,7,8-Heptachlorodibenzodioxin
1,2,3,4,6,7,8-heptachlorooxanthrene
Heptachlorodibenzo-p-dioxin
1,2,3,4,6,7,8-heptachlorinated dibenzodioxin
1,2,3,4,6,7,8-HpCDD
1,2,3,4,6,7,8-H7CDD

Chemical & Physical Properties

[ Density]:
1.834g/cm3

[ Boiling Point ]:
503.3ºC at 760 mmHg

[ Molecular Formula ]:
C12HCl7O2

[ Molecular Weight ]:
425.30600

[ Flash Point ]:
189.6ºC

[ Exact Mass ]:
421.78000

[ PSA ]:
18.46000

[ LogP ]:
8.15840

[ Index of Refraction ]:
1.67

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP3190000
CHEMICAL NAME :
Dibenzo-p-dioxin, 1,2,3,4,6,7,8-heptachloro-
CAS REGISTRY NUMBER :
35822-46-9
BEILSTEIN REFERENCE NO. :
1630271
LAST UPDATED :
199806
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H-Cl7-O2
MOLECULAR WEIGHT :
425.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6325 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 66,471,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSSID2 Pergamon Series on Environmental Science. (Oxford, UK) V.1-7, 1978-82. Discontinued. Volume(issue)/page/year: 5,367,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
364 mg/kg/13W-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in platelet count Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 14,271,1994 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997

Safety Information

[ RIDADR ]:
UN 2811

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2932999060

Customs

[ HS Code ]: 2932999060

[ Summary ]:
2932999060. Dioxin,Furan(polychorinated dibenzo-p-dioxines,polychlorinated dibenzofurans). VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods). MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 1,2,3,4,6,7,8-HCDF
  • 1,2,3,4,6,7,9-Heptachlorodibenzo-p-dioxin
  • Octachlorooxanthrene
  • OCTABROMIDIBENZO-PARA-DIOXIN
  • Dibenzo[b,e][1,4]dioxin-d8
  • (2H8)-9H-Fluoren-9-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-{1-[3-(Difluoromethoxy)-4-methylphenyl]cyclopropyl}ethan-1-amine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-Ethyl-4-[4-(propan-2-yl)phenyl]pyrrolidine-3-carboxylic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine