2,8-Bis(trifluoromethyl)quinolin-4-ol

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Names

[ CAS No. ]:
35853-41-9

[ Name ]:
2,8-Bis(trifluoromethyl)quinolin-4-ol

[Synonym ]:
4-Quinolinol, 2,8-bis(trifluoromethyl)-
T66 BM EVJ CXFFF JXFFF
2,5-DIMETHYLPYRROLE-3-CARBOXYLIC ACID
2,8-Bis(trifluoromethyl)-4-hydroxyquinoline
2,8-di(trifluoromethyl)quinolin-4-ol
EINECS 252-762-0
2,8-Bis(trifluormethyl)chinolin-4-ol
2,8-bis(trifluoromethyl)quinolin-4-ol
2,8-Bis(trifluoromethyl)quinolin-4(1H)-one
MFCD00075091
2,8-Bis(trifluoromethyl)-4-quinolinol
T66 BNJ CXFFF EQ JXFFF

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
305.9±37.0 °C at 760 mmHg

[ Melting Point ]:
130-134 °C(lit.)

[ Molecular Formula ]:
C11H5F6NO

[ Molecular Weight ]:
281.154

[ Flash Point ]:
138.8±26.5 °C

[ Exact Mass ]:
281.027527

[ PSA ]:
33.12000

[ LogP ]:
4.73

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.505

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ WGK Germany ]:
3

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl trifluoroacetoacetate
  • 2-Aminobenzotrifluoride

DownStream

  • 4-Bromo-2,8-bis(trifluoromethyl)quinoline
  • bis[2,8-di(trifluoromethyl)quinolin-4-yl-2-pyridyl] ketone
  • Mefloquine hydrochloride
  • 4-chloro-2,8-di(trifluoromethyl)quinoline
  • 2,8-BIS(TRIFLUOROMETHYL)-4-VINYLQUINOLINE
  • 4-iodo-2,8-bis(trifluoromethyl)quinoline
  • alpha-2-pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol
  • alpha,2-pyridyl-2,8-bis(trifluoromethyl)quinoline-4-acetonitrile
  • 2-[2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLYL]OXIRANE

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2,8-Bis-trifluoromethyl-quinolin-4-yl)-pyridin-3-yl-methanone
  • (2,8-BIS-TRIFLUOROMETHYL-QUINOLIN-4-YL)-PIPERIDIN-2-YL-METHANOL HYDROCHLORIDE(R*,R*)
  • [2,8-bis(trifluoromethyl)quinolin-4-yl]methanol
  • 2,8-Bis(trifluoromethyl)quinolin-4(1H)-one
  • 2,8-bis(trifluoromethyl)quinolin-4-amine
  • 2,8-bis(trifluoromethyl)quinolin-4-yl 4-methylbenzenesulfonate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-(4-Bromo-2-(trifluoromethyl)phenyl)propan-1-one
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide