Pregna-1,4-diene-3,20-dione,9,21-difluoro-11,17-dihydroxy-6-methyl-, (6a,11b)- (9CI)

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Names

[ CAS No. ]:
359-80-8

[ Name ]:
Pregna-1,4-diene-3,20-dione,9,21-difluoro-11,17-dihydroxy-6-methyl-, (6a,11b)- (9CI)

[Synonym ]:
C-912
Naugatuck C-912
U.S. Rubber C-912
Uniroyal C-912

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
540.7ºC at 760 mmHg

[ Molecular Formula ]:
C22H28F2O4

[ Molecular Weight ]:
394.45200

[ Flash Point ]:
280.8ºC

[ Exact Mass ]:
394.19600

[ PSA ]:
74.60000

[ LogP ]:
2.87290

[ Index of Refraction ]:
1.563

Synthetic Route

Precursor & DownStream

Precursor

  • Pregna-1, 4-diene-3,20-dione, 9-fluoro-11.beta.,17, 21-trihydroxy-6.alpha.-methyl-, 21-acetate
  • Prednisolone, 9-bromo-6.alpha.-methyl-, 21-acetate
  • 21-acetoxy-9,11β-epoxy-17-hydroxy-6α-methyl-9β-pregna-1,4-diene-3,20-dione
  • Pregna-1,4-diene-3,20-dione, 21-fluoro-11.beta., 17-dihydroxy-6.alpha.-methyl-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)-
  • Methylprednisolone
  • Pregna-1,4,9(11)-triene-3,20-dione,21-(acetyloxy)-17-hydroxy-6-methyl-, (6a)-
  • methylprednisolone acetate

DownStream