NECA
Suppliers
Names
[ CAS No. ]:
35920-39-9
[ Name ]:
NECA
[Synonym ]:
(2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide (non-preferred name)
(2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydro-2-furancarboxamide (non-preferred name)
5’-Ethylcarboxamido Adenosine
MFCD00069195
5'-Ethylcarboxamido Adenosine
1-(6-AMINO-9H-PURIN-9-YL)-1-DEOXY-N-ETHYL-β-D-RIBOFURANURONAMIDE
β-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-
5'-(N-Ethylcarboxamido)adenosine
NECA
Chemical & Physical Properties
[ Density]:
1.9±0.1 g/cm3
[ Melting Point ]:
229-231ºC
[ Molecular Formula ]:
C12H16N6O4
[ Molecular Weight ]:
308.293
[ Exact Mass ]:
308.123291
[ PSA ]:
148.41000
[ LogP ]:
-0.48
[ Index of Refraction ]:
1.829
[ Water Solubility ]:
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL Solutions may be stored for several days at 4?#x00b0;C.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VJ2232000
- CHEMICAL NAME :
- Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-, hemihydrate
- CAS REGISTRY NUMBER :
- 35920-39-9
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H16-N6-O4.1/2H2-O
- MOLECULAR WEIGHT :
- 317.35
- WISWESSER LINE NOTATION :
- T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ EVM2 &QH 1/2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,313,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,313,1980
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300
[ Precautionary Statements ]:
P264-P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+: Very toxic;
[ Risk Phrases ]:
R28
[ Safety Phrases ]:
22-26-36-45
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
VJ2232000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2934999090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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