1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione

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Names

[ CAS No. ]:
35959-38-7

[ Name ]:
1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione

[Synonym ]:
5'-Amino-2',5'-dideoxyuridin
5'-Amino-2'-deoxyuridine
5'-NH2-2'-dU
Uridine,5'-amino-2',5'-dideoxy
5'-amino-2',5'-dideoxyuridine

Chemical & Physical Properties

[ Density]:
1.466g/cm3

[ Molecular Formula ]:
C9H13N3O4

[ Molecular Weight ]:
227.22

[ Exact Mass ]:
227.09100

[ PSA ]:
110.34000

[ Index of Refraction ]:
1.601

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5’-Azido-2’,5’-dideoxyuridine
  • 2'-deoxyuridine
  • 5'-o-(dimethoxytrityl)-5-(propargyloxy)-2'-deoxyuridine
  • Aqueous ammonia

DownStream

  • 2-bromo-N-[[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl]acetamide
  • Uracil
  • Uridine 5'-diphosphate

Related Compounds

  • [(2,5-Dimethyl-3-thienyl)methyl]methylamine hydrochloride
  • (4-(Pyrrolidin-1-ylmethyl)phenyl)boronic acid hydrochloride
  • ([1-(5-Chloro-2-thienyl)cyclohexyl]methyl)amine hydrochloride
  • N-[(4-methyl-1H-imidazol-5-yl)methyl]propan-2-amine dihydrochloride
  • N-((2-Methyl-1H-indol-3-yl)methyl)cyclopropanamine hydrochloride
  • N-(2-((Dimethylamino)methyl)benzyl)cyclopropanamine dihydrochloride
  • (9H-Fluoren-9-yl)methyl 4-hydrazinylpiperidine-1-carboxylate 2,2,2-trifluoroacetate
  • Sodium 2-(pyrrolidin-1-ylmethyl)-1,3-thiazole-4-carboxylate
  • 1-{[(5-Methyl-1,3-thiazol-2-yl)methyl]-amino}propan-2-ol dihydrochloride
  • [(1-Ethyl-1H-imidazol-2-yl)methyl](2-furylmethyl)-amine dihydrochloride
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