1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione

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Names

[ CAS No. ]:
35959-38-7

[ Name ]:
1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione

[Synonym ]:
5'-Amino-2',5'-dideoxyuridin
5'-Amino-2'-deoxyuridine
5'-NH2-2'-dU
Uridine,5'-amino-2',5'-dideoxy
5'-amino-2',5'-dideoxyuridine

Chemical & Physical Properties

[ Density]:
1.466g/cm3

[ Molecular Formula ]:
C9H13N3O4

[ Molecular Weight ]:
227.22

[ Exact Mass ]:
227.09100

[ PSA ]:
110.34000

[ Index of Refraction ]:
1.601

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5’-Azido-2’,5’-dideoxyuridine
  • 2'-deoxyuridine
  • 5'-o-(dimethoxytrityl)-5-(propargyloxy)-2'-deoxyuridine
  • Aqueous ammonia

DownStream

  • 2-bromo-N-[[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl]acetamide
  • Uracil
  • Uridine 5'-diphosphate

Related Compounds

  • 2-[2-(2,4,5-Trifluorophenyl)ethyl]oxirane
  • {6-Oxaspiro[2.5]octan-1-yl}methyl 4-methylbenzene-1-sulfonate
  • 1-[2-(2,5-Dimethylphenyl)propan-2-yl]cyclopropan-1-amine
  • rac-(1R,2R)-2-(2-fluoro-3-nitrophenyl)cyclopropane-1-carboxylic acid
  • 1-(2-Fluoro-6-methylphenyl)-3-hydroxycyclobutane-1-carboxylic acid
  • Methyl 2-amino-2-(5-cyanothiophen-2-yl)acetate
  • 1-[4-Methyl-5-(2-methyloxiran-2-yl)-1,3-thiazol-2-yl]piperidine
  • 4-(2-Ethynylphenyl)butan-2-one
  • 2-[1-(1,1-Dioxo-1lambda6-thiolan-3-yl)cyclopropyl]-2-methoxyacetic acid
  • Methyl 2-amino-3-cyclohexyl-3-methylbutanoate
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