1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione

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Names

[ CAS No. ]:
35959-38-7

[ Name ]:
1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-oxolan-2-yl]pyrimidine-2,4-dione

[Synonym ]:
5'-Amino-2',5'-dideoxyuridin
5'-Amino-2'-deoxyuridine
5'-NH2-2'-dU
Uridine,5'-amino-2',5'-dideoxy
5'-amino-2',5'-dideoxyuridine

Chemical & Physical Properties

[ Density]:
1.466g/cm3

[ Molecular Formula ]:
C9H13N3O4

[ Molecular Weight ]:
227.22

[ Exact Mass ]:
227.09100

[ PSA ]:
110.34000

[ Index of Refraction ]:
1.601

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5’-Azido-2’,5’-dideoxyuridine
  • 2'-deoxyuridine
  • 5'-o-(dimethoxytrityl)-5-(propargyloxy)-2'-deoxyuridine
  • Aqueous ammonia

DownStream

  • 2-bromo-N-[[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl]acetamide
  • Uracil
  • Uridine 5'-diphosphate

Related Compounds

  • 5-Bromo-2-1,2,4-triazol-1-yl-benzaldehyde
  • 4-Hydroxy-5,8-dimethyl-carbostyril
  • 4-Hydroxy-2-oxo-1,2-dihydroquinoline-8-carboxylic acid
  • 4-Chloro-2-1,2,4-triazol-1-yl-benzaldehyde
  • 4-(2-Chloropyrimidin-4-ylthio)benzenamine
  • Methyl[2-(6-methylpyridin-3-yl)ethyl]amine
  • 1,2-Dihydro-4-hydroxy-1,6-dimethyl-2-oxo-N-[3-(trifluoromethyl)phenyl]-3-pyridinecarboxamide
  • Tert-butyl [2-(4-chloro-3-fluorophenyl)-1-(6-chloropyridin-3-yl)-1-methyl-2-oxoethyl]carbamate
  • N-[[1-[[(phenylmethoxy)carbonyl]amino]cyclopropyl]carbonyl]-N-(phenylmethyl)glycine methyl ester
  • Tert-butyl [1-(6-chloropyridin-3-yl)-1-methyl-2-oxoethyl]carbamate