4-(1,3-DIOXOISOINDOLIN-2-YL)BUTANAL

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Names

[ CAS No. ]:
3598-60-5

[ Name ]:
4-(1,3-DIOXOISOINDOLIN-2-YL)BUTANAL

[Synonym ]:
4-Phthalimidobutyraldehyde
4-Phthalimidobutanal

Chemical & Physical Properties

[ Density]:
1.274g/cm3

[ Boiling Point ]:
373.9ºC at 760 mmHg

[ Molecular Formula ]:
C12H11NO3

[ Molecular Weight ]:
217.22100

[ Flash Point ]:
173.7ºC

[ Exact Mass ]:
217.07400

[ PSA ]:
54.45000

[ LogP ]:
1.19960

[ Index of Refraction ]:
1.576

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5175000
CHEMICAL NAME :
Phthalimide, N-(3-formylpropyl)-
CAS REGISTRY NUMBER :
3598-60-5
BEILSTEIN REFERENCE NO. :
0011926
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H11-N-O3
MOLECULAR WEIGHT :
217.24
WISWESSER LINE NOTATION :
T56 BVNVJ C3VH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1055 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 57,815,1968

Safety Information

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(4-Hydroxybutyl)-2H-isoindole-1,3-dione
  • Oxalyl chloride
  • 1-(2-Phthalimidobutanoyl)chloride
  • N-carbethoxyphthalimide
  • 2-but-3-enylisoindoline-1,3-dione
  • Phthalic anhydride
  • 4-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)butanoic acid
  • 1H-Isoindole-1,3(2H)-dione,2-(2-propen-1-yl)-
  • carbon monoxide

DownStream

  • 1H-Isoindole-1,3(2H)-dione,2-[2-(1H-indol-3-yl)ethyl]-
  • 2-[2-(2-Amino-1,3-thiazol-5-yl)ethyl]-1H-isoindole-1,3(2H)-dione hydrobromide
  • NAN-190 hydrobromide
  • 2,3,4,10b-tetrahydro-1H-pyrido[1,2-b]isoindol-6-one
  • 2-[3-(1,3-dithian-2-yl)propyl]isoindole-1,3-dione
  • 2-[4-[((S)-5,6,7,8-Tetrahydroquinolin-8-yl)amino]butyl]isoindole-1,3-dione
  • 2-[2-(5-nitro-1H-indol-3-yl)ethyl]isoindole-1,3-dione

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • (2S,3R)-2,3-bis(benzyloxy)-4-(1,3-dioxoisoindolin-2-yl)butanal
  • (2S,3S)-2,3-bis(benzyloxy)-4-(1,3-dioxoisoindolin-2-yl)butanal
  • 4-((1,3-dioxoisoindolin-2-yl)methyl)-3-fluorobenzonitrile
  • 4-(1,3-dioxoisoindolin-2-yl)-N-(thiazol-2-yl)benzenesulfonamide
  • 4-(1,3-dioxoisoindolin-2-yl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
  • 4-(1,3-Dioxoisoindolin-2-yl)butane-1-sulfonyl chloride