ecdysone

Suppliers

Names

[ Name ]:
ecdysone

[Synonym ]:
MFCD00042683
A-ECDYSONE
[3H]-Ecdysone
Ecdysone
EINECS 222-760-4
(2β,3β,5β,22R)-2,3,14,22,25-pentahydroxycholest-7-en-6-one
Gynostemma Gypenosides
α-Ecdysone

Chemical & Physical Properties

[ Density]:
1.22g/cm3

[ Boiling Point ]:
632ºC at 760mmHg

[ Melting Point ]:
242°C

[ Molecular Formula ]:
C₂₇H₄₄O₆

[ Molecular Weight ]:
464.63500

[ Flash Point ]:
350ºC

[ Exact Mass ]:
464.31400

[ PSA ]:
118.22000

[ LogP ]:
2.73910

[ Index of Refraction ]:
1.582

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FZ8170000

CHEMICAL NAME :: 5-beta-Cholest-7-en-6-one, 2-beta,3-beta,14,22,25-pentahydroxy-, (20S,22R)-

CAS REGISTRY NUMBER :: 3604-87-3

BEILSTEIN REFERENCE NO. :: 2422986

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C27-H44-O6

MOLECULAR WEIGHT :: 464.71

WISWESSER LINE NOTATION :: L E5 B666 JUTJ A1 E1 FY1&2YQXQ1&1 IQ OQ PQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Amphibian - toad

DOSE/DURATION :: 50 mg/kg/17W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Insect - not otherwise specified

DOSE/DURATION :: 200 ppm

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 30,279,1974

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
FZ8170000

[ HS Code ]:
2937290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2aS,4R,5S,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-10-(3-methoxy-3-oxopropyl)-6a,8a,9-trimethyl-2-oxooctadecahydro-1H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,5-diyl diacetate
(2aS,4R,5S,6aR,6bR,8aS,8bR,9S,10R,11aS,12aR)-10-(3-methoxy-3-oxopropyl)-6a,8a,9-trimethyl-2-oxo-2a,3,4,5,6,6a,6b,7,8,8a,8b,9,10,11a,12,12a-hexadecahydro-2H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,5-diyl diacetate
(2aS,4R,5S,6aR,6bR,8aR,8bR,9S,10R,11aS)-10-(3-methoxy-3-oxopropyl)-6a,8a,9-trimethyl-2-oxo-2a,3,4,5,6,6a,6b,7,8,8a,8b,9,10,11a-tetradecahydro-2H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,5-diyl diacetate
(1S,2aS,4R,5S,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-1-bromo-10-(3-methoxy-3-oxopropyl)-6a,8a,9-trimethyl-2-oxooctadecahydro-1H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,5-diyl diacetate
(2aS,4R,5S,6aR,6bR,8aR,8bR,9S,10R,11aS,12aS)-12a-hydroxy-10-(3-methoxy-3-oxopropyl)-6a,8a,9-trimethyl-2-oxo-2a,3,4,5,6,6a,6b,7,8,8a,8b,9,10,11a,12,12a-hexadecahydro-2H-naphtho[2',1':4,5]indeno[2,1-b]furan-4,5-diyl diacetate
(2S,3R,5S,9R,10R,13R,17R)-10,13-dimethyl-6-oxo-17-((S)-1-((R)-5-oxotetrahydrofuran-2-yl)ethyl)-2,3,4,5,6,7,9,10,11,12,13,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-2,3-diyl diacetate
(2S,3R,5S,9R,10R,13R,14S,17R)-14-hydroperoxy-10,13-dimethyl-6-oxo-17-((S)-1-((R)-5-oxotetrahydrofuran-2-yl)ethyl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-2,3-diyl diacetate
(2S,3R,5S,10R,13R,14S,17R)-14-hydroxy-10,13-dimethyl-6-oxo-17-((S)-1-((R)-5-oxotetrahydrofuran-2-yl)ethyl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-2,3-diyl diacetate

DownStream

Customs

[ HS Code ]: 2937290090

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β-ecdysone
B-ECDYSONE
22-Isoecdysone
β-Ecdysone 2-acetate
Ecdysone 2,3-acetonide
ecdysone 2-hemisuccinate
benzyl N-[3-methyl-1-(4-nitrophenyl)-1H-pyrazol-5-yl]carbamate
5-(1-bromo-2-methoxyethyl)-1-methyl-1H-1,2,3-triazole
2-{[(benzyloxy)carbonyl]amino}-3-(7-methyl-1H-indol-3-yl)propanoic acid
Benzyl 4'-oxo-3',4'-dihydrospiro[piperidine-4,2'-pyrano[3,2-b]pyridine]-1-carboxylate
benzyl N-[2-hydroxy-3-(1-oxo-1,2-dihydroisoquinolin-2-yl)propyl]carbamate
Benzyl 4-(4-cyano-2-cyclopropyl-1,3-oxazol-5-yl)piperazine-1-carboxylate
4-Benzyl 1-(tert-butyl) 2-(fluoromethyl)piperazine-1,4-dicarboxylate
Methyl 3-{[(benzyloxy)carbonyl]amino}-4-hydroxy-5-methylbenzoate
2-{[(Benzyloxy)carbonyl]amino}-2-[4-(hydroxymethyl)phenyl]acetic acid
Ethyl 5-{[(benzyloxy)carbonyl]amino}-2-hydroxybenzoate