4-Benzyl-3-(butylamino)-5-sulfamoylbenzoic acid

Names

[ CAS No. ]:
36148-38-6

[ Name ]:
4-Benzyl-3-(butylamino)-5-sulfamoylbenzoic acid

[Synonym ]:
Besunida [INN-Spanish]
Besunida [Spanish]
Besunidum [Latin]
4-Benzyl-3-n-butylamino-5-sulfamylbenzoic acid
Besunidum [INN-Latin]
Besunide
pINN
4-Benzyl-3-butylamino-5-sulfamoylbenzoic acid

Chemical & Physical Properties

[ Density]:
1.297g/cm3

[ Boiling Point ]:
620.3ºC at 760mmHg

[ Molecular Formula ]:
C18H22N2O4S

[ Molecular Weight ]:
362.44300

[ Flash Point ]:
328.9ºC

[ Exact Mass ]:
362.13000

[ PSA ]:
117.87000

[ LogP ]:
4.68910

[ Index of Refraction ]:
1.611

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG3100500
CHEMICAL NAME :
Benzoic acid, 3-(aminosulfonyl)-4-benzyl-5-(butylamino)-
CAS REGISTRY NUMBER :
36148-38-6
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H22-N2-O4-S
MOLECULAR WEIGHT :
362.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1170,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
186 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1170,1973

Safety Information

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

  • 4-(3-aminophenoxy)-3-(butylamino)-5-sulfamoylbenzoic acid
  • 4-(4-aminophenoxy)-3-(butylamino)-5-sulfamoylbenzoic acid
  • 4-(3-acetamidophenoxy)-3-n-butylamino-5-sulfamoylbenzoic acid
  • 4-(4-aminophenyl)sulfanyl-3-(butylamino)-5-sulfamoylbenzoic acid
  • 4-benzyl-3,5-dimethylphenol,phosphorous acid
  • 4-benzyl-3,5-dimethylphenol,phosphoric acid