2',3'-o-isopropylideneuridine

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Names

[ CAS No. ]:
362-43-6

[ Name ]:
2',3'-o-isopropylideneuridine

[Synonym ]:
EINECS 206-647-7
2',3'-O-Isopropylideneuridine
MFCD00034509

Chemical & Physical Properties

[ Density]:
1.376g/cm3

[ Boiling Point ]:
426.76°C (rough estimate)

[ Melting Point ]:
163-166ºC

[ Molecular Formula ]:
C12H16N2O6

[ Molecular Weight ]:
284.26500

[ Exact Mass ]:
284.10100

[ PSA ]:
102.78000

[ Index of Refraction ]:
1.539

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • Acetone
  • Uridine
  • 2',3'-O-isopropylidene-5'-O-TBDMS-uridine
  • 2,2-Dimethoxypropane
  • Uridine,2',3'-O-(1-methylethylidene)-5'-O-(triphenylmethyl)-
  • Triethyl orthoformate
  • Thymidine, 3-benzoyl-
  • 5-cyano-1-(2,3-O-isopropylidene-β-D-ribofuranosyl)uracil
  • 2',3'-O-(isopropylidene)uridine 5'-acetate

DownStream

  • 2,2'-Cyclouridine
  • 1-[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]-1,3-diazinane-2,4-dione
  • Uridine monophosphate
  • Uridine
  • 5-(Hydroxymethyl)uridine
  • Uridine triphosphate
  • Uridine 5'-diphosphate
  • 2',3'-O-(isopropylidene)uridine 5'-acetate
  • 6-Iodouridine
  • 1-β-D-Arabinofuranosyluracil

Articles

5'-Uridyl derivatives of N-glycosyl allophanic acid and biuret.

Carbohydr. Res. 345 , 163-167, (2010)

(2',3'-O-Isopropylidene-5'-uridyl) 4-(2,3,4,6-tetra-O-acetyl-beta-d-glycopyranosyl)allophanates were obtained in the reactions of 2',3'-O-isopropylidene-uridine and O-peracetylated beta-d-gluco-, gala...

New methods for the synthesis of N-benzoylated uridine and thymidine derivatives; a convenient method for N-debenzoylation.

Carbohydr. Res. 337 , 369-372, (2002)

An improved procedure for the synthesis of N-benzoyl-2',3'-O-isopropylidene uridine via one-step selective N-benzoylation of 2',3' -O-isopropylidene uridine has been developed. An efficient synthetic ...

Synthesis and central nervous system depressant effects of N3-substituted 2',3'-O-isopropylideneuridines.

Chem. Pharm. Bull. 47 , 1802-1804, (1999)

N3-Substituted derivatives of 2',3'-O-isopropylideneuridine (1) were synthesized and their pharmacological effects on the central nervous system (CNS) examined using mice. Methyl (2), ethyl (3), propy...


More Articles


Related Compounds

  • 5-bromo-2',3'-O-isopropylideneuridine
  • 5-cyano-2',3'-O-isopropylideneuridine
  • 5-methyl-2',3'-O-isopropylideneuridine
  • 5-Fluoro-2',3'-O-isopropylideneuridine
  • 5-formyl-2',3'-O-isopropylideneuridine
  • 5'-deoxy-2',3'-O-isopropylideneuridine
  • Methyl 2-((3-bromophenyl)sulfonyl)propanoate
  • Tert-butyl 2-[(5,6-dichloropyridine-3-carbonyl)amino]acetate
  • {1-[(2,5-difluorophenyl)methyl]-1H-1,2,3-triazol-4-yl}methanamine
  • 1-Bromo-3-[(2-chloroethyl)sulfanyl]benzene
  • 2-(5,6-difluoro-2-methyl-1H-1,3-benzodiazol-1-yl)acetic acid
  • 1-Bromo-3-(2-chloroethanesulfonyl)benzene
  • 1-Bromo-3-(3-bromopropanesulfonyl)benzene
  • O-(4-Methylphenyl)-L-serine
  • 4-((Trimethylsilyl)ethynyl)thiophen-2-ylboronic acid
  • 1H-Benzimidazole, 2-(1,1-dimethylpropyl)-5,6-difluoro-