Jatrorrhizine

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Names

[ Name ]:
Jatrorrhizine

[Synonym ]:
Neprotine
YATROIZINE HCL
Neprotin
Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-
3-Hydroxy-2,9,10-trimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium
3-Hydroxy-2,9,10-trimethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolinium
NEPROTINE IODIDE
Jateorrhizine
Jatrorrhizine
jatorrhizine
Jateorhizine
Jatrorrhizin
NEPROTINE HCL
7,8,13,13a-Tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium
Yatrorizine

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₀NO₄+

[ Molecular Weight ]:
338.377

[ Exact Mass ]:
338.138672

[ PSA ]:
51.80000

[ LogP ]:
-1.89

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50

[ Safety Phrases ]:
61

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Effect of jatrorrhizine on delayed gastrointestinal transit in rat postoperative ileus.

J. Pharm. Pharmacol. 64(3) , 413-9, (2012)

Postoperative ileus is major cause of postoperative complication and prolonged hospitalization. Jatrorrhizine, which is a protoberberine alkaloid isolated from the medicinal plants Berberis aristata a...

Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein.

Xenobiotica 41(4) , 290-6, (2011)

The absorption and transport mechanisms of berberine, palmatine, jateorhizine, and coptisine were studied using a Caco-2 cells uptake and transport model, with the addition of cyclosporin A and verapa...

Pharmacokinetics and metabolism of jatrorrhizine, a gastric prokinetic drug candidate.

Biopharm. Drug Dispos. 33(3) , 135-45, (2012)

Jatrorrhizine, a protoberberine alkaloid derived from Coptis chinensis, is currently under investigation as a natural gastric prokinetic drug candidate. In vitro and in vivo studies were conducted to ...

jatrorrhizine
jatrorrhizine iodide
jatrorrhizine hcl(rg)
Jatrorrhizine chloride
jatrorrhizine chloride
Jatrorrhizinehydroxide
1-Chloro-3-(propan-2-yloxy)-5-(trifluoromethoxy)benzene
N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)cyclobutanecarboxamide
N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)benzamide
N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)thiophene-2-carboxamide
2-(2,5-dioxopyrrolidin-1-yl)-N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)acetamide
3-(Difluoromethyl)-2-methoxyisonicotinonitrile
2,4-difluoro-N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)benzamide
2-(4-fluorophenoxy)-N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)acetamide
4-propyl-N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)-1,2,3-thiadiazole-5-carboxamide
2-(2-methoxyphenoxy)-N-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)acetamide

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