4-(chloromethyl)-2-phenyl-1,3-dioxolane

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Names

[ CAS No. ]:
36236-72-3

[ Name ]:
4-(chloromethyl)-2-phenyl-1,3-dioxolane

[Synonym ]:
1,3-DIOXOLANE,4-CHLOROMETHYL-2-PHENYL
2-phenyl-4-chloronethyl-1,3-dioxolane
4-Chlormethyl-2-phenyl-[1,3]dioxolan
1-Chlor-2,3-dihydroxy-propan-benzyliden-diether
4-Chloromethyl-2-phenyl-1,3-dioxolane

Chemical & Physical Properties

[ Density]:
1.186g/cm3

[ Boiling Point ]:
298.5ºC at 760 mmHg

[ Molecular Formula ]:
C10H11ClO2

[ Molecular Weight ]:
198.64600

[ Flash Point ]:
124.7ºC

[ Exact Mass ]:
198.04500

[ PSA ]:
18.46000

[ LogP ]:
2.33940

[ Index of Refraction ]:
1.521

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JH6980000
CHEMICAL NAME :
1,3-Dioxolane, 4-chloromethyl-2-phenyl-
CAS REGISTRY NUMBER :
36236-72-3
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H11-Cl-O2
MOLECULAR WEIGHT :
198.66
WISWESSER LINE NOTATION :
T5O COTJ BR& D1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
75 mg/kg
SEX/DURATION :
male 30 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 30,117,1972

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzaldehyde
  • Epichlorohydrin
  • 3-Chloro-1,2-propanediol
  • 2-phenyl-1,3-benzodioxole
  • 2-phenyl-4,5-trans-tetrametylene-1,3-dioxolan
  • 5-methyl-2-phenyl-1,3-dioxolan-4-one

DownStream

  • 1-Benzoyloxy-3-chloropropan-2-ol
  • 1-chloro-3-hydroxy-2-propyl benzoate
  • benzoic acid,1,3-dichloropropan-2-ol
  • Benzaldehyde
  • 4-methylidene-2-phenyl-1,3-dioxolane

Related Compounds

  • 4-(chloromethyl)-2-phenyl-1,3-thiazole-5-carbonyl chloride
  • 4-(chloromethyl)-2-phenyl-1,3-dithiolane
  • 4-(Chloromethyl)-2-phenyl-1,3-thiazole
  • 4-(chloromethyl)-2-methyl-2-phenyl-1,3-dioxolane
  • 4-(chloromethyl)-2-[(4-chlorophenyl)methyl]-2-phenyl-1,3-dioxolane
  • 4-(chloromethyl)-2-[4-[4-(chloromethyl)-1,3-dioxolan-2-yl]phenyl]-1,3-dioxolane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-(2-Nitrophenyl)cyclopentane-1-carboxylic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-{5-benzyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl}-3,6-dichloropyridine-2-carboxamide
  • tert-Butyl-DL-alanine