beta-Piperidinoethyl benzhydryl ether hydrochloride

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Names

[ Name ]:
beta-Piperidinoethyl benzhydryl ether hydrochloride

[Synonym ]:
1-(2-Benzhydryloxy-aethyl)-piperidin
1-(2-benzhydryloxy-ethyl)-piperidine
<2-Piperidino-ethyl>-diphenylmethyl-ether
1-Piperidino-2-benzhydryloxy-ethan
1-(2-benzhydryloxy-ethyl)-piperidine,hydrochloride
Perastine
1-<2-Diphenylmethoxy-ethyl>-piperidin
1-(2-Benzhydryloxy-aethyl)-piperidin,Hydrochlorid
Perastinhydrochlorid
Perastine [INN]

Chemical & Physical Properties

[ Boiling Point ]:
407.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₆ClNO

[ Molecular Weight ]:
331.88000

[ Flash Point ]:
176.8ºC

[ Exact Mass ]:
331.17000

[ PSA ]:
12.47000

[ LogP ]:
5.01840

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7760000

CHEMICAL NAME :: Piperidine, 1-(2-(diphenylmethoxy)ethyl)-, hydrochloride

CAS REGISTRY NUMBER :: 3626-66-2

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H25-N-O.Cl-H

MOLECULAR WEIGHT :: 331.92

WISWESSER LINE NOTATION :: T6NTJ A2OYR&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 102,250,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 97 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,709,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 83,120,1945

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 13,326,1948

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

1-(5-Bromopyrimidin-2-yl)-3,3-difluorocyclobutan-1-amine
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
1-(Chloromethyl)-1-(2-methoxy-2-methylpropyl)cyclobutane
(2S,3S)-2-{[(1RS,3SR)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexyl]formamido}-3-methylpentanoic acid
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
2-(1-ethyl-1H-pyrazol-3-yl)-2,2-difluoroethan-1-amine
(2R)-2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-enamido]-2-phenylacetic acid