4-Methylhistamine dihydrochloride

Suppliers

Names

[ Name ]:
4-Methylhistamine dihydrochloride

[Synonym ]:
2-<5-methyl-1H-imidazol-4-yl>ethanamine dihydrochloride
5-metilistamina diclorinato
5-Methylhistamine dihydrochloride
5-Methyl-1H-imidazole-4-ethanamine dihydrochloride
2-methylhistamine dihydrochloride
5-metilistamina dicloridrato
4-Methylhistamine dihydrochloride

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Boiling Point ]:
345ºC at 760 mmHg

[ Molecular Formula ]:
C₆H₁₃Cl₂N₃

[ Molecular Weight ]:
198.09400

[ Flash Point ]:
189.3ºC

[ Exact Mass ]:
197.04900

[ PSA ]:
54.70000

[ LogP ]:
2.52360

[ Index of Refraction ]:
1.558

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI3505800

CHEMICAL NAME :: Imidazole, 4-(2-aminoethyl)-5-methyl-, dihydrochloride

CAS REGISTRY NUMBER :: 36376-47-3

LAST UPDATED :: 199206

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H11-N3.2Cl-H

MOLECULAR WEIGHT :: 198.12

WISWESSER LINE NOTATION :: T5M CNJ D2Z E1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 991 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - pleural effusion

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 77,54,1943

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 198 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 77,54,1943

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-[5-methyl-1-(phenylmethyl)-1H-imidazol-4-yl]ethanamine
5-methyl-1-(phenylmethyl)-1H-imidazole-4-carboxaldehyde
nona-2,6-dienal semicarbazone
ethyl 1-benzyl-5-methylimidazole-4-carboxylate
2-[5-methyl-1-(phenylmethyl)-1H-imidazol-4-yl]ethanone oxime
2-[5-methyl-1-(phenylmethyl)-1H-imidazol-4-yl]-1-nitroethene

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%