5'-Thymidylic acid

Suppliers

Names

[ CAS No. ]:
365-07-1

[ Name ]:
5'-Thymidylic acid

[Synonym ]:
deoxytmp
thymidinephosphate
DTMP
5-Methyl-dUMP
TMP SODIUM SALT
Thymidine, mono(dihydrogen phosphate) (ester)
MFCD00067349
TMP DISODIUM SALT
DTMP 2NA

Chemical & Physical Properties

[ Density]:
1.654 g/cm3

[ Molecular Formula ]:
C10H15N2O8P

[ Molecular Weight ]:
322.20800

[ Exact Mass ]:
322.05700

[ PSA ]:
160.89000

[ Index of Refraction ]:
1.592

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XP2090000
CHEMICAL NAME :
5'-Thymidylic acid
CAS REGISTRY NUMBER :
365-07-1
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H15-N2-O8-P
MOLECULAR WEIGHT :
322.24
WISWESSER LINE NOTATION :
T6NVMVTJ E1 A- ET5OTJ B1OPQQO CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Unscheduled DNA synthesis
TEST SYSTEM :
Rodent - mouse Fibroblast
DOSE/DURATION :
1 mmol/L
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,797,1986

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Thymidine
  • 5'-thymidyl 2-(1,4-naphthoquinonyl)methyl N-methyl-N-(4-chlorobutyl) phosphoramidate
  • dUMP
  • 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-[(4-methoxyphenyl)-diphenylmethoxy]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[5-(diaminophosphoryloxymethyl)-4-hydroxy-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
  • SP-thymidylyl-3',5'-thymidine phosphoromonothiolate
  • RP-thymidylyl-3',5'-thymidine phosphoromonothiolate
  • thymidine 5'-4-nitrophenyl phosphate

DownStream

  • Disodium 5'-O-phosphonatothymidine
  • TDP-Glucose
  • Thymine
  • Thymidine

Related Compounds

  • 5'-Thymidylic acid,a-oxo
  • 5'-Thymidylic acid,6-bromo
  • 5'-Thymidylic acid,3'-acetate
  • 5'-Thymidylic Acid Calcium Salt
  • 5'-Thymidylic Acid Disodium Salt
  • 5'-Thymidylic acid,dibutyl ester
  • [1-(3-Chlorophenyl)ethyl](2,2,2-trifluoroethyl)amine
  • N-(1,4-dioxaspiro[4.5]decan-2-ylmethyl)-5-ethylthiophene-2-sulfonamide
  • (1-methyl-1H-1,2,3-triazol-4-yl)(4-phenylpiperazin-1-yl)methanone
  • 5-(2-Hydroxyethoxy)-2-propylisoquinolin-1(2H)-one
  • 1-methyl-N-(4-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide
  • 1-((1H-benzo[d]imidazol-2-yl)methyl)-N-benzylpiperidine-4-carboxamide
  • 1-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-bromo-3-methylphenyl)piperidine-4-carboxamide
  • 1-((1H-benzo[d]imidazol-2-yl)methyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidine-4-carboxamide
  • 2-(4-((2,5-dimethylphenyl)sulfonyl)piperazin-1-yl)-1-methyl-1H-benzo[d]imidazole
  • 1-methyl-2-(4-((3-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)-1H-benzo[d]imidazole
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.