Etidocaine Hydrochloride

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Names

[ CAS No. ]:
36637-19-1

[ Name ]:
Etidocaine Hydrochloride

[Synonym ]:
Duranest Hydrochloride
Etidocaine HCl
Etidocaine hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
389.7ºC at 760 mmHg

[ Molecular Formula ]:
C17H29ClN2O

[ Molecular Weight ]:
312.87800

[ Flash Point ]:
189.5ºC

[ Exact Mass ]:
312.19700

[ PSA ]:
35.83000

[ LogP ]:
5.20390

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EU5435000
CHEMICAL NAME :
2',6'-Butyroxylidide, 2-(N-ethylpropylamino)-, hydrochloride, (+-)-
CAS REGISTRY NUMBER :
36637-19-1
LAST UPDATED :
199109
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C17-H28-N2-O.Cl-H
MOLECULAR WEIGHT :
312.93

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
64400 ug/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - somnolence (general depressed activity)
REFERENCE :
AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 60,385,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
99 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 61,1829,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 61,1829,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
58178 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 21,277,1990
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,13,1976

Related Compounds

  • Etidocaine-d9 hydrochloride
  • etidocaine
  • Triprolidine hydrochloride
  • Tyrocidine, hydrochloride
  • Fasudil Hydrochloride Hydrate
  • dodecylamine hydrochloride
  • Androst-4-en-3-one, 17-propoxy-
  • 1-Iodo-4-(triethylsilyl)benzene
  • 6-Amino-9H-purine-8-acetic acid
  • Phenyl 2-(2-bromoethyl)benzoate
  • 10H-Phenoxazine, 2,10-diacetyl-
  • 2,2-Dimethyl-7,8-bis(phenylmethoxy)-6-[[2-(trimethylsilyl)ethoxy]methoxy]-4H-1,3-benzodioxin
  • D-Histidine, N-formyl-1-methyl-
  • 1,1a(2)-Biphenyl-2,2a(2),4,4a(2),6,6a(2)-d6
  • Secoradiatine, deoxyoxo-, oxime
  • Ethyl 5-ethyl-2-propylbenzoate
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