Etidocaine Hydrochloride

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Names

[ CAS No. ]:
36637-19-1

[ Name ]:
Etidocaine Hydrochloride

[Synonym ]:
Duranest Hydrochloride
Etidocaine HCl
Etidocaine hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
389.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₉ClN₂O

[ Molecular Weight ]:
312.87800

[ Flash Point ]:
189.5ºC

[ Exact Mass ]:
312.19700

[ PSA ]:
35.83000

[ LogP ]:
5.20390

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EU5435000

CHEMICAL NAME :: 2',6'-Butyroxylidide, 2-(N-ethylpropylamino)-, hydrochloride, (+-)-

CAS REGISTRY NUMBER :: 36637-19-1

LAST UPDATED :: 199109

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C17-H28-N2-O.Cl-H

MOLECULAR WEIGHT :: 312.93

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 64400 ug/kg

TOXIC EFFECTS :: Behavioral - anticonvulsant Behavioral - somnolence (general depressed activity)

REFERENCE :: AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 60,385,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 99 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 61,1829,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 61,1829,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 58178 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 21,277,1990

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,13,1976

Related Compounds

Etidocaine-d9 hydrochloride
etidocaine
Triprolidine hydrochloride
Tyrocidine, hydrochloride
Fasudil Hydrochloride Hydrate
dodecylamine hydrochloride
Acetamide, 2-[[5-[(2-methoxyethyl)amino]-1,3,4-thiadiazol-2-yl]thio]-N-(2-methylcyclohexyl)-
3-(2-aminoethyl)thieno[3,2-d]pyrimidin-4(3H)-one
N-4-Piperidinyl-2-propynamide
2-Oxo-N-(piperidin-4-yl)-1,2-dihydropyridine-3-carboxamide
4-Amino-4-(5-methylthiophen-2-yl)butanoic acid
2,3-Dichloro-N-4-piperidinylbenzamide
2-(4-hydroxyphenyl)-N-(piperidin-4-yl)acetamide
5-Methyl-N-(piperidin-4-yl)-1,2-oxazole-3-carboxamide
N-(piperidin-4-yl)oxane-4-carboxamide
3-Methyl-N-(piperidin-4-yl)-1,2-oxazole-5-carboxamide

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