Etidocaine Hydrochloride
Suppliers
Names
[ CAS No. ]:
36637-19-1
[ Name ]:
Etidocaine Hydrochloride
[Synonym ]:
Duranest Hydrochloride
Etidocaine HCl
Etidocaine hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
389.7ºC at 760 mmHg
[ Molecular Formula ]:
C17H29ClN2O
[ Molecular Weight ]:
312.87800
[ Flash Point ]:
189.5ºC
[ Exact Mass ]:
312.19700
[ PSA ]:
35.83000
[ LogP ]:
5.20390
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EU5435000
- CHEMICAL NAME :
- 2',6'-Butyroxylidide, 2-(N-ethylpropylamino)-, hydrochloride, (+-)-
- CAS REGISTRY NUMBER :
- 36637-19-1
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C17-H28-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 312.93
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 64400 ug/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant Behavioral - somnolence (general depressed activity)
- REFERENCE :
- AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 60,385,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 99 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 61,1829,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6700 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 61,1829,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58178 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 21,277,1990
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,13,1976
Related Compounds
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