2-Hydroxy-3-naphtoamide

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Names

[ CAS No. ]:
3665-51-8

[ Name ]:
2-Hydroxy-3-naphtoamide

[Synonym ]:
3-Hydroxy-2-naphthamide
3-Hydroxy-5,6,7,8-tetrahydro-2-naphthoic Amide
3-hydroxy-2-aminocarbonylnaphthalene
3-hydroxy-2-naphthalenecarboxamide
2-NAPHTHAMIDE,3-HYDROXY
2-hydroxynaphthalene-3-carboxamide
2-Hydroxy-3-naphthoamide
3-hydroxy-naphthalene-2-carboxylic acid amide
2-Hydroxy-3-naphthamide
MFCD00082972
2-Naphthalenecarboxamide,3-hydroxy
EINECS 222-926-6
2-Hydroxy-3-naphthalenecarboxamide

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
426.4ºC at 760mmHg

[ Melting Point ]:
211-216ºC

[ Molecular Formula ]:
C11H9NO2

[ Molecular Weight ]:
187.19500

[ Flash Point ]:
211.7ºC

[ Exact Mass ]:
187.06300

[ PSA ]:
63.32000

[ LogP ]:
2.34460

[ Index of Refraction ]:
1.708

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK7000000
CHEMICAL NAME :
2-Naphthamide, 3-hydroxy-
CAS REGISTRY NUMBER :
3665-51-8
BEILSTEIN REFERENCE NO. :
1104926
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H9-N-O2
MOLECULAR WEIGHT :
187.21
WISWESSER LINE NOTATION :
L66J CVZ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26;S37/S39

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-acetoxy-2-naphthoic acid chloride
  • 2-Naphthalenecarboxylicacid, 3-(acetyloxy)-
  • 3-Hydroxy-2-naphthoic acid
  • 3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
  • 2-Cyano-3-hydroxynaphthalene
  • 3-hydroxy-2-naphthoyl chloride
  • 3-methoxy-[2]naphthoic acid amide
  • 3-methoxynaphthalene-2-carbonitrile
  • Urea

DownStream

  • 2-Cyano-3-hydroxynaphthalene

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 2-hydroxy-3-[(E)-9-methoxytridec-10-en-6-yl]cyclohexa-2,5-diene-1,4-dione
  • 2-Hydroxy-3-tert-butylacetophenone
  • 2-hydroxy-3,4-dimethoxy-6-methylbenzaldehyde
  • [2-hydroxy-3-[3-[2-hydroxy-3-(trimethylazaniumyl)propoxy]phenoxy]propyl]-trimethylazanium,diiodide
  • 2-hydroxy-3,4,5-triiodobenzoyl chloride
  • 2-hydroxy-3-[[(4-methylphenyl)sulphonyl]oxy]propyl tert-decanoate