2,4-Difluorophenol

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Names

[ CAS No. ]:
367-27-1

[ Name ]:
2,4-Difluorophenol

[Synonym ]:
2,4-Difluor-phenol
4-Difluorophenol
QR BF DF
2,4-Difluorbenzolol
2,4-difluorophenyl
2.4-Difluor-1-hydroxy-benzol
2,4-difluorophenole
EINECS 206-688-0
MFCD00009715
Phenol, 2,4-difluoro-
2,4-Difluorophenol
2,4-difluoro-phenol
Phenol,2,4-difluoro

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
145.7±0.0 °C at 760 mmHg

[ Melting Point ]:
22.4 °C(lit.)

[ Molecular Formula ]:
C6H4F2O

[ Molecular Weight ]:
130.09

[ Flash Point ]:
56.7±0.0 °C

[ Exact Mass ]:
130.023026

[ PSA ]:
20.23000

[ LogP ]:
2.04

[ Vapour Pressure ]:
3.8±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.496

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302 + H312 + H332-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R11;R20/21/22;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S16

[ RIDADR ]:
1992

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2907199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(tert-butyldimethylsilyloxy)-2,4-difluorobenzene
  • 2,4-Difluorophenylboronic acid
  • 2,4-Difluoroaniline
  • Phenol
  • 2',4'-Difluoroacetophenone
  • 2,4-Difluorobenzaldehyde
  • 1,3-Difluorobenzene
  • 2,4-Difluoro-1-methoxybenzene
  • Acetic acid,2-(2,4-difluorophenoxy)-
  • Hydrogen iodide

DownStream

  • 2,4-difluoro-6-nitrophenol
  • 2,4-Difluoro-1-methoxybenzene
  • 1-(Benzyloxy)-2,4-difluorobenzene
  • Acetic acid,2-(2,4-difluorophenoxy)-
  • Acetic acid,2-(2-chloro-4,6-difluorophenoxy)-
  • 2,4-difluoro-1-(4-nitrophenoxy)benzene
  • 2-(2,4-difluorophenoxy)-1-(4-methylsulfanylphenyl)ethanone
  • 3,5-difluoro-2-hydroxybenzoic acid
  • 2-Bromo-4,6-difluorophenol
  • 3,5-Difluoro-2-hydroxybenzaldehyde

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Synthesis of novel fluorinated coumarins: excellent UV-light excitable fluorescent dyes.

Bioorg. Med. Chem. Lett. 8(22) , 3107-10, (1998)

Two new fluorinated fluorescent dyes, 6,8-difluoro-7-hydroxy-4-methylcoumarin (Marina Blue) and 3-carboxy-6,8-difluoro-7-hydroxycoumarin (Pacific Blue), exhibit excellent photophysical properties amon...

Genetically determined differences in noradrenergic input to the brain cortex: a histochemical and biochemical study in two inbred strains of mice.

Neuroscience 4(7) , 877-88, (1979)


More Articles

Related Compounds

  • 2,4-difluorophenole
  • 5-Bromo-2,4-difluorophenol
  • 5-amino-2,4-difluorophenol
  • 6-Amino-2,4-difluorophenol
  • 3-Ethoxy-2,4-difluorophenol
  • 3-Carboxy-2,4-difluorophenol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine