1,1-Di-tert-butoxy-N,N-dimethylmethanamine

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Names

[ Name ]:
1,1-Di-tert-butoxy-N,N-dimethylmethanamine

[Synonym ]:
N,N-Dimethyl-1,1-bis[(2-methyl-2-propanyl)oxy]methanamine
N,N-Dimethylformamide Di-tert-butyl Acetal
1,1-Di-tert-butoxy-N,N-dimethylmethanamine
N,N-dimethyl-1,1-bis[(2-methylpropan-2-yl)oxy]methanamine
1,1-Di-Tert-Butoxytrimethylamine
1,1-Di-tert-butoxy-N,N-dimethylmethy
Methanamine, 1,1-bis(1,1-dimethylethoxy)-N,N-dimethyl-
MFCD00015002
EINECS 253-222-7
N,N-DIMETHYL FORMAMIDE DI-TERT-BUTYL ACETAL

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
175.2±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₂₅NO₂

[ Molecular Weight ]:
203.322

[ Flash Point ]:
33.9±0.0 °C

[ Exact Mass ]:
203.188522

[ PSA ]:
21.70000

[ LogP ]:
3.20

[ Vapour Pressure ]:
1.2±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.435

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

potassium t-butoxide
[(dimethylamino)methylene]dimethylammonium methyl sulphate
N,N,N',N'-Tetramethylformamidinium-(p-toluolsulfonat)
N,N-Dimethylformamide dimethyl acetal
tert-Butanol
bis(dimethylamino)acetonitrile
tert-Butoxy bis(dimethylamino)methane

DownStream

DI-TERT-BUTYL GLUTARATE
4-Quinazolinone
4-(1,1-dimethylethoxy)quinazoline
3-(1,1-dimethylethyl)quinazolin-4-one
t-butyl 6-bromo-3-pyridinecarboxylate
Benzoic acid, 4-nitro-,1,1-dimethylethyl ester
tert-butyl 2-hydroxybenzoate
tert-butyl 2-(tert-butoxy)benzoate
tert-Butyl 2-chloroisonicotinate
TERT-BUTYL 3-(((BENZYLOXY)CARBONYL)AMINO)PROPANOATE

Articles

Simultaneous determination of cocaine and benzoyl ecgonine in urine by gas chromatography with on-column alkylation.

J. Forensic Sci. 22(1) , 7-16, (1977)

A gas chromatographic procedure has been developed for the simultaneous determination of cocaine and benzoyl ecgonine in urine specimens. The two drugs are extracted by isopropanol/chloroform from uri...

Synthesis and pharmacology of metabolically stable tert-butyl ethers of morphine and levorphanol.

J. Med. Chem. 25(10) , 1264-6, (1982)

3-O-tert-Butylmorphine (5) was prepared from 6-O-acetylmorphine (3) via alkylation with N,N-dimethylformamide di-tert-butyl acetal, followed by hydrolytic removal of the 3-(dimethylamino)-2-propenoate...

Synthesis and biodistribution of (11)C-GW7845, a positron-emitting agonist for peroxisome proliferator-activated receptor-{gamma}.

J. Nucl. Med. 46(10) , 1719-26, (2005)

The goal of this study was to synthesize and evaluate in vivo the peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist (11)C-GW7845 ((S)-2-(1-carboxy-2-{4-[2-(5-methyl-2-phenyloxazol-4...

[1,1'-Biphenyl]-2,2'-dimethanamine,5,5'-bis(1,1-dimethylethyl)-N2,N2,N2',N2'-tetramethyl-
N,N-dimethyl-1-[(2-methylpropan-2-yl)oxy]prop-2-en-1-amine
2-[2-chloro-1-[(2-methylpropan-2-yl)oxy]ethenoxy]-2-methylpropane
1,1-di-tert-butyl-1-chloro-N-(di-tert-butylsilylene)silanamine
1,1-bis(3,5-di-tert-butylphenyl)hydrazine
1,1-di(4-chlorophenyl)hydrazine