Puerarin

Suppliers

Names

[ Name ]:
Puerarin

[Synonym ]:
8-(β-D-Glucopyranosyl)-4',7-dihydroxyisoflavone
Puerarin std.
Puerqarin
4H-1-Benzopyran-4-one, 8-(β-D-glucopyranosyloxy)-7-hydroxy-3-(4-hydroxyphenyl)-
Pueraria flavonoids
MFCD00076007
7-Hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl β-D-glucopyranoside
Puerain
Puerarine
Kakonein
daidzein-8-C-glucose
Purerarin
7-Hydroxy-3-(4-hydroxyphenyl)-8-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-on
7-Hydroxy-3-(4-hydroxyphényl)-8-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one
7-Hydroxy-3-(4-hydroxyphenyl)-8-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-one
PUERARIN
7-Hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl b-D-glucopyranoside
Puararin
7-Hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl-β-D-glucopyranoside

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
791.2±60.0 °C at 760 mmHg

[ Melting Point ]:
187-189°C

[ Molecular Formula ]:
C₂₁H₂₀O₉

[ Molecular Weight ]:
416.38

[ Flash Point ]:
281.5±26.4 °C

[ PSA ]:
160.82000

[ LogP ]:
-0.67

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.717

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO5216000

CHEMICAL NAME :: Puerarin

CAS REGISTRY NUMBER :: 3681-99-0

BEILSTEIN REFERENCE NO. :: 0064198

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H20-O9

MOLECULAR WEIGHT :: 416.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 738 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 6,166,1985

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F,C

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
22-24/25-45-36/37/39-26-16

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UO5216000

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The transgenic Arabidopsis plant system, pER8-GFP, as a powerful tool in searching for natural product estrogen-agonists/antagonists.

J. Nat. Prod. 68 , 971-3, (2005)

The transgenic Arabidopsis plant system, pER8-GFP, may be used as a powerful tool in searching for natural estrogen-agonists/antagonists. Among selected plant extracts and natural products, the method...

UFLC-MS/MS method for simultaneous determination of luteolin-7-O-gentiobioside, luteolin-7-O-β-D-glucoside and luteolin-7-O-β-D-glucuronide in beagle dog plasma and its application to a pharmacokinetic study after administration of traditional Chinese medicinal preparation: Kudiezi injection.

J. Pharm. Biomed. Anal. 72 , 127-33, (2013)

A rapid, sensitive and selective ultra-fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) method for the simultaneous determination of three active flavonoid glycosides: luteolin-7-O-gen...

Glucose uptake enhancing activity of puerarin and the role of C-glucoside suggested from activity of related compounds.

Bioorg. Med. Chem. Lett. 20 , 4333-6, (2010)

Chemical treatment of diabetes mellitus is widely studied and controlling of blood glucose level is the main course of therapy. In type 2 diabetes mellitus, insulin resistance is the major problem. An...

Puerarin
Puerarin apioside
3'-Methoxypuerarin
3'-Hydroxypuerarin
Puerarin 6''-O-xyloside
4',7-di-O-methylpuerarin
(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl 1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxylate
1-{[4-(Furan-3-yl)thiophen-2-yl]methyl}-3-(2-methoxyethyl)urea
6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-[1-(isoquinoline-1-carbonyl)piperidin-4-yl]-2,3-dihydropyridazin-3-one
5-Bromothieno[2,3-b]thiophene-2-carboxylic acid
(3R)-3-Amino-3-(4-methyl-1,2,3-thiadiazol-5-yl)propanamide
2-[3-(4,4-Difluoropiperidine-1-carbonyl)piperidin-1-yl]acetamide
3-(3-Chlorophenyl)-N-[[4-(furan-3-yl)thiophen-2-yl]methyl]propanamide
2-(benzylsulfanyl)-N-{[4-(furan-3-yl)thiophen-2-yl]methyl}acetamide
2-(4-chlorophenoxy)-N-{[4-(furan-3-yl)thiophen-2-yl]methyl}acetamide
1-(3,3-Dimethylpiperazin-1-yl)-3-fluoropropan-2-ol

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