Centrophenoxine hydrochloride
Suppliers
Names
[ CAS No. ]:
3685-84-5
[ Name ]:
Centrophenoxine hydrochloride
[Synonym ]:
Acetic acid, (p-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride
EINECS 222-975-3
Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride
2-(Dimethylamino)ethyl (p-chlorophenoxy)acetate hydrochloride
MFCD00012533
Clocete
Acetic acid, (p-chlorophenoxy)-, 2-(dimethylamino)ethyl ester hydrochloride
Centrophenoxine hydrochloride
Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride (9CI)
2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate,hydrochloride
2-(Dimethylamino)ethyl 4-Chlorophenoxyacetate Hydrochloride
2-(Dimethylamino)ethyl (4-chlorophenoxy)acetate hydrochloride (1:1)
Meclofenoxate Hydrochloride
Acetic acid, 2-(4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride (1:1)
Meclofenoxate (hydrochloride)
Chemical & Physical Properties
[ Boiling Point ]:
345.9ºC at 760mmHg
[ Melting Point ]:
133-135°C
[ Molecular Formula ]:
C12H17Cl2NO3
[ Molecular Weight ]:
294.174
[ Exact Mass ]:
293.058563
[ PSA ]:
38.77000
[ LogP ]:
2.62560
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG0440000
- CHEMICAL NAME :
- Acetic acid, (p-chlorophenoxy)-, 2-dimethylaminoethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 3685-84-5
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H16-Cl-N-O3.Cl-H
- MOLECULAR WEIGHT :
- 294.20
- WISWESSER LINE NOTATION :
- GR DO1VO2N1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 865 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KSKZAN Khimiya v Sel'skom Khozyaistve. Chemistry in Agriculture. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1963- Volume(issue)/page/year: 16(2),59,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 153,1914,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 660 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,814,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,814,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #398M
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 153,1914,1959
Safety Information
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S26-S36
[ RTECS ]:
AG0440000
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%