1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

Names

[ Name ]:
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

[Synonym ]:
1,6-DIHYDRO-1-METHYL-6-OXOPYRIDINE-3-CARBOXYLIC ACID
1-methyl-6-oxopyridine-3-carboxylic acid
Nudifloric acid
1,6-Dihydro-1-methyl-6-oxo-3-pyridinecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.381g/cm3

[ Boiling Point ]:
329.6ºC at 760mmHg

[ Molecular Formula ]:
C₇H₇NO₃

[ Molecular Weight ]:
153.13500

[ Flash Point ]:
153.2ºC

[ Exact Mass ]:
153.04300

[ PSA ]:
59.30000

[ LogP ]:
0.08350

[ Index of Refraction ]:
1.577

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

6-Hydroxynicotinic acid
methyl iodide
3-Pyridinecarboxamide,1,6-dihydro-6-imino-1-methyl-(9CI)
1-methylpyridinium-3-carb(ox)aldehyde
Pyridinium,3-(aminocarbonyl)-1-methyl-, iodide (1:1)
5-acetyl-1-methylpyridin-2-one
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester
Pyridine,3-(2-methyl-1,3-dioxolan-2-yl)-
5-(Carbomethoxy)-2-pyrone

DownStream

3-Pyridinecarboxylicacid, 1,6-dihydro-1-methyl-6-oxo-, ethyl ester
6-Chloronicotinic acid
Methyl 6-chloronicotinate
1-methyl-5-nitro-6-oxopyridine-3-carboxylic acid
1-Methyl-3,5-dinitro-2(1H)-pyridinone
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
1-Methyl-5-cyanopyridine-2(1H)-one
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee.

J. Pharm. Biomed. Anal. 30(3) , 773-80, (2002)

Caffeine metabolites were extracted from urine samples collected 4 h after consumption of a cup of coffee and were separated by high-performance liquid chromatography (HPLC) on a C18 (5 microm) revers...

Urinary excretion of N1-methyl-2-pyridone-5-carboxylic acid and the fate of remaining of trigonelline.

Adv. Exp. Med. Biol. 398 , 599-603, (1996)

Nicotinamide and insulin sensitivity.

Diabetologia 36(4) , 369, (1993)

N'-(4-chlorobenzo[d]thiazol-2-yl)-4-(morpholinosulfonyl)benzohydrazide
N'-(4-chlorobenzo[d]thiazol-2-yl)-2-(thiophen-2-yl)quinoline-4-carbohydrazide
N'-(4-chlorobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzohydrazide
N'-(4-chlorobenzo[d]thiazol-2-yl)-4-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)benzohydrazide
N'-(4-chlorobenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide
N'-(4-chlorobenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzohydrazide
N'-(4-chlorobenzo[d]thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carbohydrazide
N'-(6-methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzohydrazide
4-((2,6-dimethylmorpholino)sulfonyl)-N'-(6-methoxybenzo[d]thiazol-2-yl)benzohydrazide
N'-(6-methoxybenzo[d]thiazol-2-yl)-2-(thiophen-2-yl)quinoline-4-carbohydrazide

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