2-Fluoropyridine

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Names

[ CAS No. ]:
372-48-5

[ Name ]:
2-Fluoropyridine

[Synonym ]:
o-fluoropyridine
2-fluoro-pyridine
Pyridine, 2-fluoro-
2-F-pyridine
PYRIDINE,2-FLUORO
fluoropyridine
2-Fluoropyridine
EINECS 206-757-5
2-fluoranylpyridine
MFCD00006224

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
125.9±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H4FN

[ Molecular Weight ]:
97.090

[ Flash Point ]:
28.3±0.0 °C

[ Exact Mass ]:
97.032776

[ PSA ]:
12.89000

[ LogP ]:
0.84

[ Vapour Pressure ]:
14.4±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.472

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT3900000
CHEMICAL NAME :
Pyridine, 2-fluoro-
CAS REGISTRY NUMBER :
372-48-5
BEILSTEIN REFERENCE NO. :
0001515
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H4-F-N
MOLECULAR WEIGHT :
97.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
5 mg/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 176,185,1987

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S16

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UT3900000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Pyridine
  • 2-Chloropyridine
  • 2-Aminopyridine
  • 2-Bromopyridine
  • pyridyl diazonium fluoride
  • Perfluoro-2-methyl-2-pentene
  • 2(5H)-Pyridinone(9CI)
  • 2-pyridone
  • 1-Fluoropyridinium trifluoromethanesulfonate
  • BUTYRONITRILE

DownStream

  • 2,4-Difluoropyridine
  • Phenyl(2-pyridinyl)acetonitrile
  • 2-F-pyridineH+
  • 1,1-BIS(METHYLTHIO)ETHYLENE
  • 2-fluoro-1-methylpyridinium p-toluenesulfonate
  • 3-Bromo-2-fluoropyridine
  • 2-Fluoro-4-bromopyridine
  • 3,4-Dibromo-2-fluoropyridine
  • 2-(Benzyloxy)pyridine
  • 2-(2-thienyl)pyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The many roles for fluorine in medicinal chemistry.

J. Med. Chem. 51 , 4359-69, (2008)


More Articles

Related Compounds

  • 2-Fluoropyridine-3-c
  • 2-fluoropyridine-H(1+)
  • 2-fluoropyridine,hydrate
  • 5-Amino-2-fluoropyridine
  • 4-Cyano-2-fluoropyridine
  • 5-nitro-2-fluoropyridine
  • 2-chloro-N-(1,2-diphenylethyl)-6-methylpyridine-3-carboxamide
  • Sohirnone A
  • 4-Bromo-5-nitro-2-thiophenemethanol
  • 9Kyt3JV5W2
  • (2-Methanesulfonylphenyl)methanesulfonyl chloride
  • Ethyl 2-chloro-4-pentafluoroethyl-5-thiazolecarboxylate
  • Phosphonic acid, (3-oxocyclohexyl)-, dimethyl ester
  • 3-(Azetidin-3-yl)phenol
  • 1-methyl-3-(2-(piperidin-1-yl)ethyl)-9-(m-tolyl)-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione
  • 9-benzyl-1,7-dimethyl-3-(2-oxopropyl)-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione
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