Complement factor D

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Names

[ CAS No. ]:
37213-56-2

[ Name ]:
Complement factor D

Chemical & Physical Properties

[ Storage condition ]:
−70°C

Safety Information

[ Hazard Codes ]:
B

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.

J. Mol. Biol. 282 , 1061-1081, (1998)

Factor D is a serine protease essential for the activation of the alternative pathway of complement. The structures of native factor D and a complex formed with isatoic anhydride inhibitor were determ...

Immune evasion of Enterococcus faecalis by an extracellular gelatinase that cleaves C3 and iC3b.

J. Histochem. Cytochem. 181 , 6328-36, (2008)

Enterococcus faecalis (Ef) accounts for most cases of enterococcal bacteremia, which is one of the principal causes of nosocomial bloodstream infections (BSI). Among several virulence factors associat...

Complement factor D in age-related macular degeneration.

Invest. Ophthalmol. Vis. Sci. 52 , 8828-8834, (2011)

To examine the role of complement factor D (CFD) in age-related macular degeneration (AMD) by analysis of genetic association, copy number variation, and plasma CFD concentrations.Single nucleotide po...

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