1,8-Diaminooctane

Suppliers

Names

[ CAS No. ]:
373-44-4

[ Name ]:
1,8-Diaminooctane

[Synonym ]:
MFCD00008248
Octamethylenediamine
1,8-Diaminooctane
octane-1,8-diamine
EINECS 206-764-3
1,8-Octanediamine

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
240.5±8.0 °C at 760 mmHg

[ Melting Point ]:
50-52 °C(lit.)

[ Molecular Formula ]:
C8H20N2

[ Molecular Weight ]:
144.258

[ Flash Point ]:
165.0±0.0 °C

[ Exact Mass ]:
144.162643

[ PSA ]:
52.04000

[ LogP ]:
1.10

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.462

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
575 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RG8841500
CHEMICAL NAME :
1,8-Octanediamine
CAS REGISTRY NUMBER :
373-44-4
BEILSTEIN REFERENCE NO. :
1735426
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H20-N2
MOLECULAR WEIGHT :
144.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,751,1992
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,751,1992 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,751,1992

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45-S37/39

[ RIDADR ]:
UN 3259 8/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
RG8841500

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29212900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Octandinitril
  • 1,8-Octanediol
  • Sebacoyl chloride
  • N,N'-octane-1,8-diyl-bis-phthalimide
  • Sebacic dihydrazide
  • decanediamide
  • Decanedioic acid
  • N,N'-(octane-1,8-diyl)bis(2,2,2-trifluoroacetamide)
  • decanedioyl azide
  • 1,8-DIISOCYANATOOCTANE

DownStream

  • METHOCTRAMINE HYDROCHLORIDE
  • 1,8-Octane diisothiocyanate
  • 2-cyano-N-[8-[(2-cyanoacetyl)amino]octyl]acetamide
  • 1,1'-(1,8-Octanediyl)bisguanidine
  • 1,10-diazacyclooctadecane
  • 1,8-BIS(MALEIMIDE)OCTANE
  • N'-(1,2,3,4-tetrahydroacridin-9-yl)octane-1,8-diamine
  • 1,7-dichlorooctane
  • 1,8-Dichlorooctane
  • 1-Boc-1,8-diaminooctane

Customs

[ HS Code ]: 2921290000

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Paralcaligenes ginsengisoli sp. nov., isolated from ginseng cultivated soil.

Antonie van Leeuwenhoek 108 , 619-26, (2015)

A novel bacterial strain DCY104(T) isolated from soil of a ginseng field in Yeoncheon County, Republic of Korea is described in this study. Cells were short rod-shaped, motile by mean of one polar fla...

Enhanced transcellular penetration and drug delivery by crosslinked polymeric micelles into pancreatic multicellular tumor spheroids.

Biomater. Sci. 3 , 1085-95, (2015)

Many attempts have been made in the application of multicellular tumor spheroids (MCTS) as a 3D tumor model to investigate their biological responses upon introduction of polymeric micelles as nanocar...

An easy-to-use excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine, for use in the highly sensitive and selective liquid chromatography analysis of histamine in Japanese soy sauces.

Anal. Chim. Acta 880 , 145-51, (2015)

In this study, a novel pre-column excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine (CMPT), was developed for polyamines, specifically histamine. ...


More Articles

Related Compounds

  • 1,8-diaminooctane
  • 1,8-diaminooctane*2HCl
  • 1-Boc-1,8-diaminooctane
  • N-dansyl-1,8-diaminooctane
  • N,N'-ditosyl-1,8-diaminooctane
  • N,N'-dimethyl-1,8-diaminooctane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-{2-[4-(pentylamino)-1H-pyrazol-1-yl]ethoxy}ethan-1-ol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide